Nuclear magnetic resonance (NMR) in biochemistry: Applications to enzyme systems / Raymond A. Dwek

Public ISBD Titre : Nuclear magnetic resonance (NMR) in biochemistry: Applications to enzyme systems Type de document : texte imprimé Auteurs : Raymond A. Dwek, Auteur Editeur : Oxford : Clarendon Press Année de publication : 1973 Collection : Monographs on Physical Biochemistry Importance : 395 p. ISBN/ISSN/EAN : 978-0-19-854614-6 Langues : Anglais (eng) Catégories : Technologies, Méthodes, Réactions Tags : NUCLEAR MAGNETIC RESONANCE  ENZYMES-Analysis Index. décimale : B-B Résumé : "How far can one use n.m.r. to determine the complete three-dimensional structure, of an enzyme in solution ? Can n.m.r. studies help to identify functional groups involved in catalysis, the nature of the transition state, and the role of any metal ions and co factors, etc ? What are the limitations of n.m.r. and in cases wh ere structural information of the enzyme itself cannot be obtained, can n.m.r. help ? Can the stereochemical relationships between ligand sites on allosteric enzymes be determine ? What aspects of n.m.r. are sensitive to different conformational states of an enzyme ? How do the use of paramagnetic probes and chemical modifications make the solution of these problems easier ? This book attempts to answer some of these questions-and by suitable examples tries to discuss and assess the information that the different types of magnetic resonance measurements can give. The use of paragmagnetic ions as probes features prominently in this book, and the section on this is intended to serve as a handbook to the biochemist and biophysicist. A brief introduction on the use of spin labels is also included. Because the methods described are applicable to most systems this book will also appeal to the chemist-particularly those whose studies involve the use of paramagnetic ions." Cote : B-B011(SdS) Num_Inv : 169 Nuclear magnetic resonance (NMR) in biochemistry: Applications to enzyme systems [texte imprimé] / Raymond A. Dwek, Auteur . - Oxford : Clarendon Press, 1973 . - 395 p.. - (Monographs on Physical Biochemistry) . ISBN : 978-0-19-854614-6 Langues : Anglais (eng) Catégories : Technologies, Méthodes, Réactions Tags : NUCLEAR MAGNETIC RESONANCE  ENZYMES-Analysis Index. décimale : B-B Résumé : "How far can one use n.m.r. to determine the complete three-dimensional structure, of an enzyme in solution ? Can n.m.r. studies help to identify functional groups involved in catalysis, the nature of the transition state, and the role of any metal ions and co factors, etc ? What are the limitations of n.m.r. and in cases wh ere structural information of the enzyme itself cannot be obtained, can n.m.r. help ? Can the stereochemical relationships between ligand sites on allosteric enzymes be determine ? What aspects of n.m.r. are sensitive to different conformational states of an enzyme ? How do the use of paramagnetic probes and chemical modifications make the solution of these problems easier ? This book attempts to answer some of these questions-and by suitable examples tries to discuss and assess the information that the different types of magnetic resonance measurements can give. The use of paragmagnetic ions as probes features prominently in this book, and the section on this is intended to serve as a handbook to the biochemist and biophysicist. A brief introduction on the use of spin labels is also included. Because the methods described are applicable to most systems this book will also appeal to the chemist-particularly those whose studies involve the use of paramagnetic ions." Cote : B-B011(SdS) Num_Inv : 169

Exemplaires(2)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
169	B-B011	Texte imprimé	Bibliothèque	Livre	Disponible
451	B-B011	Texte imprimé	Bibliothèque	Livre	Disponible

---

1 (1 - 1 / 1) Par page : 25 50 100 200