Chemical biology of neurodegeneration / Merino, Pedro

Public ISBD Titre : Chemical biology of neurodegeneration : A molecular approach Type de document : texte imprimé Auteurs : Merino, Pedro, Auteur Editeur : New York : Wiley Année de publication : 2019 Importance : 366 p. ISBN/ISSN/EAN : 978-3-527-34424-6 Langues : Anglais (eng) Catégories : Biochimie Tags : NEUROCHEMISTRY Index. décimale : B-F Résumé : Written by an experienced neurochemist, this book focuses on the main actors involved in neurodegenerative disorders at a molecular level, and places special emphasis on structural aspects and modes of action. Drawing on recent data on enzyme structure, mode of action, and inhibitor design, it describes from a biochemical point of view the six most important neurotransmitter systems and their constituent enzymes and receptors. Misfolding and aggregation of proteins within the brain is also covered. In addition, the book surveys a wide range of proven and prospective therapeutic agents that modulate key processes in the brain, from their chemical synthesis to their mode of action in model systems as well as in the patient. Note de contenu : "* Dopaminergic System * Noradrenergic System * Serotonergic System * Cholinergic System * Glutamatergic System * GABAergic system * Metabolims of main neurotransmitters * Enzymes processing neurotransmitters * Misfolded proteins * Therapeutic agents". Cote : B-F060 Num_Inv : 702 Localisation : LCC (SdS) Chemical biology of neurodegeneration : A molecular approach [texte imprimé] / Merino, Pedro, Auteur . - New York : Wiley, 2019 . - 366 p. ISBN : 978-3-527-34424-6 Langues : Anglais (eng) Catégories : Biochimie Tags : NEUROCHEMISTRY Index. décimale : B-F Résumé : Written by an experienced neurochemist, this book focuses on the main actors involved in neurodegenerative disorders at a molecular level, and places special emphasis on structural aspects and modes of action. Drawing on recent data on enzyme structure, mode of action, and inhibitor design, it describes from a biochemical point of view the six most important neurotransmitter systems and their constituent enzymes and receptors. Misfolding and aggregation of proteins within the brain is also covered. In addition, the book surveys a wide range of proven and prospective therapeutic agents that modulate key processes in the brain, from their chemical synthesis to their mode of action in model systems as well as in the patient. Note de contenu : "* Dopaminergic System * Noradrenergic System * Serotonergic System * Cholinergic System * Glutamatergic System * GABAergic system * Metabolims of main neurotransmitters * Enzymes processing neurotransmitters * Misfolded proteins * Therapeutic agents". Cote : B-F060 Num_Inv : 702 Localisation : LCC (SdS)

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
702	B-F060	Texte imprimé	Bibliothèque	Livre	Disponible

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