Titre :	Drug discovery approaches for the treatment of neurodegenerative disorders
Type de document :	texte imprimé
Auteurs :	Adejare, Adeboye, Éditeur scientifique
Editeur :	London : Academic Press
Année de publication :	2016
Importance :	ix, 290 p.
ISBN/ISSN/EAN :	978-0-12-802810-0
Note générale :	Provides a compilation of chemical considerations required in drug discovery for the treatment of neurodegenerative disorders Examines different classes of compounds currently being used in discovery and development stages Explores in vitro and in vivo models with respect to their ability to translate these models to human conditions Distills the most significant information across multiple areas of Alzheimer’s disease research to provide a single, comprehensive, and balanced resource
Langues :	Anglais (eng)
Catégories :	Biochimie
Index. décimale :	B-F
Résumé :	Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer’s Disease examines the drug discovery process for neurodegenerative diseases by focusing specifically on Alzheimer’s Disease and illustrating the paradigm necessary to ensure future research and treatment success. The book explores diagnosis, epidemiology, drug discovery strategies, current therapeutics, and much more to provide a holistic approach to the discovery, development, and treatment of Alzheimer’s Disease. Through its coverage of the latest research in targeted drug design, preclinical studies, and mouse and rat models, the book is a must-have resource for all pharmaceutical scientists, pharmacologists, neuroscientists, and clinical researchers working in this area. It illustrates why these drugs tend to fail at the clinical stage, and examines Alzheimer’s Disease within the overall context of improving the drug discovery process for the treatment of other neurodegenerative disorders.
Note de contenu :	"* General description of neurodegenerative disorders * Alzheimer’s disease diagnosis * National plan and resources to address Alzheimer’s disease * Current Medications for Treatment of Alzheimer's Disease: Acetylcholine esterase inhibitors and NMDA receptor antagonist * Physicochemical properties for potential AD drugs * Receptor approaches * Amyloid hypothesis * Tau proteins * Cholesterol and fat metabolism * Energy Metabolism * Simple in vivo models of Neurodegeneration (C. Elegans, fruitfly, and similar models) * Rodent Models * Clinical Trials * Non-pharmacologic Treatment Approaches".
Cote :	B-F051
Num_Inv :	3514
Localisation :	LCC (SdS)

Drug discovery approaches for the treatment of neurodegenerative disorders [texte imprimé] / Adejare, Adeboye, Éditeur scientifique . - London : Academic Press, 2016 . - ix, 290 p.
ISBN : 978-0-12-802810-0
Provides a compilation of chemical considerations required in drug discovery for the treatment of neurodegenerative disorders
Examines different classes of compounds currently being used in discovery and development stages
Explores in vitro and in vivo models with respect to their ability to translate these models to human conditions
Distills the most significant information across multiple areas of Alzheimer’s disease research to provide a single, comprehensive, and balanced resource
Langues : Anglais (eng)

Catégories :	Biochimie
Index. décimale :	B-F
Résumé :	Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer’s Disease examines the drug discovery process for neurodegenerative diseases by focusing specifically on Alzheimer’s Disease and illustrating the paradigm necessary to ensure future research and treatment success. The book explores diagnosis, epidemiology, drug discovery strategies, current therapeutics, and much more to provide a holistic approach to the discovery, development, and treatment of Alzheimer’s Disease. Through its coverage of the latest research in targeted drug design, preclinical studies, and mouse and rat models, the book is a must-have resource for all pharmaceutical scientists, pharmacologists, neuroscientists, and clinical researchers working in this area. It illustrates why these drugs tend to fail at the clinical stage, and examines Alzheimer’s Disease within the overall context of improving the drug discovery process for the treatment of other neurodegenerative disorders.
Note de contenu :	"* General description of neurodegenerative disorders * Alzheimer’s disease diagnosis * National plan and resources to address Alzheimer’s disease * Current Medications for Treatment of Alzheimer's Disease: Acetylcholine esterase inhibitors and NMDA receptor antagonist * Physicochemical properties for potential AD drugs * Receptor approaches * Amyloid hypothesis * Tau proteins * Cholesterol and fat metabolism * Energy Metabolism * Simple in vivo models of Neurodegeneration (C. Elegans, fruitfly, and similar models) * Rodent Models * Clinical Trials * Non-pharmacologic Treatment Approaches".
Cote :	B-F051
Num_Inv :	3514
Localisation :	LCC (SdS)