Titre :	Chemical biology of neurodegeneration : A molecular approach
Type de document :	texte imprimé
Auteurs :	Merino, Pedro, Auteur
Editeur :	New York : Wiley
Année de publication :	2019
Importance :	366 p.
ISBN/ISSN/EAN :	978-3-527-34424-6
Langues :	Anglais (eng)
Catégories :	Biochimie
Tags :	NEUROCHEMISTRY
Index. décimale :	B-F
Résumé :	Written by an experienced neurochemist, this book focuses on the main actors involved in neurodegenerative disorders at a molecular level, and places special emphasis on structural aspects and modes of action. Drawing on recent data on enzyme structure, mode of action, and inhibitor design, it describes from a biochemical point of view the six most important neurotransmitter systems and their constituent enzymes and receptors. Misfolding and aggregation of proteins within the brain is also covered. In addition, the book surveys a wide range of proven and prospective therapeutic agents that modulate key processes in the brain, from their chemical synthesis to their mode of action in model systems as well as in the patient.
Note de contenu :	"* Dopaminergic System * Noradrenergic System * Serotonergic System * Cholinergic System * Glutamatergic System * GABAergic system * Metabolims of main neurotransmitters * Enzymes processing neurotransmitters * Misfolded proteins * Therapeutic agents".
Cote :	B-F060
Num_Inv :	702
Localisation :	LCC (SdS)

Chemical biology of neurodegeneration : A molecular approach [texte imprimé] / Merino, Pedro, Auteur . - New York : Wiley, 2019 . - 366 p.
ISBN : 978-3-527-34424-6
Langues : Anglais (eng)

Catégories :	Biochimie
Tags :	NEUROCHEMISTRY
Index. décimale :	B-F
Résumé :	Written by an experienced neurochemist, this book focuses on the main actors involved in neurodegenerative disorders at a molecular level, and places special emphasis on structural aspects and modes of action. Drawing on recent data on enzyme structure, mode of action, and inhibitor design, it describes from a biochemical point of view the six most important neurotransmitter systems and their constituent enzymes and receptors. Misfolding and aggregation of proteins within the brain is also covered. In addition, the book surveys a wide range of proven and prospective therapeutic agents that modulate key processes in the brain, from their chemical synthesis to their mode of action in model systems as well as in the patient.
Note de contenu :	"* Dopaminergic System * Noradrenergic System * Serotonergic System * Cholinergic System * Glutamatergic System * GABAergic system * Metabolims of main neurotransmitters * Enzymes processing neurotransmitters * Misfolded proteins * Therapeutic agents".
Cote :	B-F060
Num_Inv :	702
Localisation :	LCC (SdS)