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Topics in molecular and structural biology
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Documents disponibles dans la collection (1)
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Titre : |
Oligodeoxynucleotides: antisense inhibitors of gene expression |
Type de document : |
texte imprimé |
Auteurs : |
Jack S. Cohen, Auteur |
Editeur : |
London : Macmillan |
Année de publication : |
1989 |
Collection : |
Topics in molecular and structural biology, ISSN 0265-4377 num. 12 |
Importance : |
xii, 255 p. |
ISBN/ISSN/EAN : |
978-0-333-49211-6 |
Langues : |
Anglais (eng) |
Tags : |
GENE EXPRESSION RNA |
Index. décimale : |
EQ -Equipe- |
Résumé : |
"The recent work on the natural occurrence of antisense RNA and subsequent use of antisense constructs to manipulate gene expression has been of enormous value to molecular biologists and it provides the bulwark behind the endeavours discussed in this publication of the state of the field." |
Note de contenu : |
"Strategies and realities; synthesis of oligonucleotides and oligonucleotide analogues; Oligodeoxynucleotides covalently linked to intercalating and reactive substances-synthesis, characterization and physicochemical studies; Inhibition of gene expression by oligonucleotides; Non-ionic antisense oligonucleotides; Phosphorothioate oligodeoxynucleotide analogues; Oligodeoxynucleotide analogues; Control of gene expression by oligodeoxynucleotides covalently linked to intercalating agents and nucleic acid-cleaving reagents; Oligonucleotides linked to reactive groups; Oligonucleotide recognition of double helical DNA by triple helix formation; Antisense oligodeoxynucleotides as a tool for studying cell regulation-mechanisms of uptake and application to the study of oncogene function; Pharmaceutical considerations." |
Cote : |
LCC/K |
Num_Inv : |
441 |
Oligodeoxynucleotides: antisense inhibitors of gene expression [texte imprimé] / Jack S. Cohen, Auteur . - London : Macmillan, 1989 . - xii, 255 p.. - ( Topics in molecular and structural biology, ISSN 0265-4377; 12) . ISBN : 978-0-333-49211-6 Langues : Anglais ( eng)
Tags : |
GENE EXPRESSION RNA |
Index. décimale : |
EQ -Equipe- |
Résumé : |
"The recent work on the natural occurrence of antisense RNA and subsequent use of antisense constructs to manipulate gene expression has been of enormous value to molecular biologists and it provides the bulwark behind the endeavours discussed in this publication of the state of the field." |
Note de contenu : |
"Strategies and realities; synthesis of oligonucleotides and oligonucleotide analogues; Oligodeoxynucleotides covalently linked to intercalating and reactive substances-synthesis, characterization and physicochemical studies; Inhibition of gene expression by oligonucleotides; Non-ionic antisense oligonucleotides; Phosphorothioate oligodeoxynucleotide analogues; Oligodeoxynucleotide analogues; Control of gene expression by oligodeoxynucleotides covalently linked to intercalating agents and nucleic acid-cleaving reagents; Oligonucleotides linked to reactive groups; Oligonucleotide recognition of double helical DNA by triple helix formation; Antisense oligodeoxynucleotides as a tool for studying cell regulation-mechanisms of uptake and application to the study of oncogene function; Pharmaceutical considerations." |
Cote : |
LCC/K |
Num_Inv : |
441 |
| |
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441
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