Titre de série :	Topics in Current Chemistry
Titre :	Vol.317 : Fragment-based drug discovery and x-ray crystallography
Type de document :	texte imprimé
Auteurs :	Thomas G. Davies, Éditeur scientifique ; Marko Hyvonen, Éditeur scientifique
Editeur :	Berlin, Heidelberg : Springer
Année de publication :	2012
Collection :	Topics in Current Chemistry, ISSN 0340-1022 num. 317
Importance :	xi, 225 p.
Format :	24 cm
ISBN/ISSN/EAN :	978-3-642-27539-5
Langues :	Anglais (eng)
Note de contenu :	"* Introduction to fragment-based drug discovery * Fragment screening using x-ray crystallography * Hsp90 inhibitors and drugs from fragment and virtual screening * Combining NMR and x-ray crystallography in fragment-based drug discovery: discovery of highly potent and selective BACE-1 inhibitors * Combining biophysical screening and x-ray crystallography for fragment-based drug discovery * Targeting protein–protein interactions and fragment-based drug discovery * Fragment screening and HIV therapeutics * Fragment-based approaches and computer-aided drug discovery."
Cote :	EXCLU (SdL)
Num_Inv :	3113

Topics in Current Chemistry. Vol.317 : Fragment-based drug discovery and x-ray crystallography [texte imprimé] / Thomas G. Davies, Éditeur scientifique ; Marko Hyvonen, Éditeur scientifique . - Berlin, Heidelberg : Springer, 2012 . - xi, 225 p. ; 24 cm. - (Topics in Current Chemistry, ISSN 0340-1022; 317) .
ISBN : 978-3-642-27539-5
Langues : Anglais (eng)

Note de contenu :	"* Introduction to fragment-based drug discovery * Fragment screening using x-ray crystallography * Hsp90 inhibitors and drugs from fragment and virtual screening * Combining NMR and x-ray crystallography in fragment-based drug discovery: discovery of highly potent and selective BACE-1 inhibitors * Combining biophysical screening and x-ray crystallography for fragment-based drug discovery * Targeting protein–protein interactions and fragment-based drug discovery * Fragment screening and HIV therapeutics * Fragment-based approaches and computer-aided drug discovery."
Cote :	EXCLU (SdL)
Num_Inv :	3113