Comprehensive Chirality. Vol.1 : Biological significance – pharmacology, phamaceutical, agrochemical / Erick M. Carreira

Public ISBD Titre de série : Comprehensive Chirality Titre : Vol.1 : Biological significance – pharmacology, phamaceutical, agrochemical Type de document : texte imprimé Auteurs : Erick M. Carreira, Éditeur scientifique ; Hisashi Yamamoto, Éditeur scientifique ; Janine R. Cossy, Éditeur scientifique Editeur : Amsterdam : Elsevier Année de publication : 2012 Collection : Comprehensive Chirality Importance : xxvi, 245 p. Format : 28 cm ISBN/ISSN/EAN : 978-0-08-095167-6 Langues : Anglais (eng) Note de contenu : "* Introduction: The importance of chirality in drugs and agrochemicals * Importance of chirality in the field of anti-infective agents * Chirality in antibacterial agents * Diastereomers, enantiomers and bioactivity. TMC207: A new candidate for the treatment of tuberculosis * Fluorine in medicinal chemistry: Importance of chirality * Peptides and chirality effects on the conformation and the synthesis of medicinally relevant peptides * Stereochemical lability in drug molecules: Cases where chirality may not be critical for drug development * Chirality in agrochemicals * The use of new phosphines as powerful tools in asymmetric synthesis of biologically active compounds * Chirality and combinatorial libraries for drug discovery, an overview." Cote : EXCLU (SdL) Num_Inv : 3290 Comprehensive Chirality. Vol.1 : Biological significance – pharmacology, phamaceutical, agrochemical [texte imprimé] / Erick M. Carreira, Éditeur scientifique ; Hisashi Yamamoto, Éditeur scientifique ; Janine R. Cossy, Éditeur scientifique . - Amsterdam : Elsevier, 2012 . - xxvi, 245 p. ; 28 cm. - (Comprehensive Chirality) . ISBN : 978-0-08-095167-6 Langues : Anglais (eng) Note de contenu : "* Introduction: The importance of chirality in drugs and agrochemicals * Importance of chirality in the field of anti-infective agents * Chirality in antibacterial agents * Diastereomers, enantiomers and bioactivity. TMC207: A new candidate for the treatment of tuberculosis * Fluorine in medicinal chemistry: Importance of chirality * Peptides and chirality effects on the conformation and the synthesis of medicinally relevant peptides * Stereochemical lability in drug molecules: Cases where chirality may not be critical for drug development * Chirality in agrochemicals * The use of new phosphines as powerful tools in asymmetric synthesis of biologically active compounds * Chirality and combinatorial libraries for drug discovery, an overview." Cote : EXCLU (SdL) Num_Inv : 3290

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
3290	EXCLU	Texte imprimé	Salle de lecture	Encyclopédie	Consultation sur place Exclu du prêt

Comprehensive Chirality. Vol.2 : Synthetic methods I – Chiral pool and diastereoselective methods / Erick M. Carreira

Public ISBD Titre de série : Comprehensive Chirality Titre : Vol.2 : Synthetic methods I – Chiral pool and diastereoselective methods Type de document : texte imprimé Auteurs : Erick M. Carreira, Éditeur scientifique ; Hisashi Yamamoto, Éditeur scientifique ; Johann H. Mulzer, Éditeur scientifique Editeur : Amsterdam : Elsevier Année de publication : 2012 Collection : Comprehensive Chirality Importance : xxiii, 782 p. Format : 28 cm ISBN/ISSN/EAN : 978-0-08-095167-6 Langues : Anglais (eng) Note de contenu : "* Introductory remarks: Chiral pool syntheses and diastereoselective reactions * General principles of diastereoselective reactions: Rigid templates * General principles of diastereoselective reactions: Diastereoselectivity via substrate-directable reactions (internal delivery) and heterocyclizations * General principles of diastereoselective reactions: Acyclic control of diastereoselectivity * General principles of diastereoselective reactions: Diastereoselective domino reactions * Chiral pool synthesis: From ?-amino acids and derivatives * Chiral pool synthesis: Starting from terpenes * Chiral pool synthesis: Chiral pool syntheses starting from carbohydrates * Chiral pool synthesis: Chiral pool syntheses from cis-cyclohexadiene diols * Chiral pool synthesis: Chiral pool synthesis from hydroxy acids: Lactic acid, tartaric acid, malic acid, and 2-methyl-3-hydroxypropionic acid * Chiral pool synthesis: Chiral pool synthesis from quinic acid * Selected diastereoselective reactions: Additions of achiral carbanions to chiral aldehydes and ketones * Selected diastereoselective reactions: Aldoltype additions * Selected diastereoselective reactions: Enolate alkylation * Selected diastereoselective reactions: Substrate controlled stereoselective conjugate addition reactions with organocopper reagents * Selected diastereoselective reactions: Free radical additions and cyclizations * Selected diastereoselective reactions: Intramolecular diels–alder reactions * Selected diastereoselective reactions: diastereoselective intra- and intermolecular 1,3-dipolar cycloadditions in natural product synthesis * Selected diastereoselective reactions: Electrocyclizations * Selected diastereoselective reactions: Ionic and zwitterionic cyclizations * Selected diastereoselective reactions: Diastereoface-differentiating claisen, cope, and [2,3]-wittig rearrangements in contemporary natural product synthesis * Selected diastereoselective reactions: Heck type cyclizations * Selected diastereoselective reactions: Gold catalyzed cyclizations * Selected diastereoselective reactions: C–H insertions." Cote : EXCLU (SdL) Num_Inv : 3291 Comprehensive Chirality. Vol.2 : Synthetic methods I – Chiral pool and diastereoselective methods [texte imprimé] / Erick M. Carreira, Éditeur scientifique ; Hisashi Yamamoto, Éditeur scientifique ; Johann H. Mulzer, Éditeur scientifique . - Amsterdam : Elsevier, 2012 . - xxiii, 782 p. ; 28 cm. - (Comprehensive Chirality) . ISBN : 978-0-08-095167-6 Langues : Anglais (eng) Note de contenu : "* Introductory remarks: Chiral pool syntheses and diastereoselective reactions * General principles of diastereoselective reactions: Rigid templates * General principles of diastereoselective reactions: Diastereoselectivity via substrate-directable reactions (internal delivery) and heterocyclizations * General principles of diastereoselective reactions: Acyclic control of diastereoselectivity * General principles of diastereoselective reactions: Diastereoselective domino reactions * Chiral pool synthesis: From ?-amino acids and derivatives * Chiral pool synthesis: Starting from terpenes * Chiral pool synthesis: Chiral pool syntheses starting from carbohydrates * Chiral pool synthesis: Chiral pool syntheses from cis-cyclohexadiene diols * Chiral pool synthesis: Chiral pool synthesis from hydroxy acids: Lactic acid, tartaric acid, malic acid, and 2-methyl-3-hydroxypropionic acid * Chiral pool synthesis: Chiral pool synthesis from quinic acid * Selected diastereoselective reactions: Additions of achiral carbanions to chiral aldehydes and ketones * Selected diastereoselective reactions: Aldoltype additions * Selected diastereoselective reactions: Enolate alkylation * Selected diastereoselective reactions: Substrate controlled stereoselective conjugate addition reactions with organocopper reagents * Selected diastereoselective reactions: Free radical additions and cyclizations * Selected diastereoselective reactions: Intramolecular diels–alder reactions * Selected diastereoselective reactions: diastereoselective intra- and intermolecular 1,3-dipolar cycloadditions in natural product synthesis * Selected diastereoselective reactions: Electrocyclizations * Selected diastereoselective reactions: Ionic and zwitterionic cyclizations * Selected diastereoselective reactions: Diastereoface-differentiating claisen, cope, and [2,3]-wittig rearrangements in contemporary natural product synthesis * Selected diastereoselective reactions: Heck type cyclizations * Selected diastereoselective reactions: Gold catalyzed cyclizations * Selected diastereoselective reactions: C–H insertions." Cote : EXCLU (SdL) Num_Inv : 3291

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
3291	EXCLU	Texte imprimé	Salle de lecture	Encyclopédie	Consultation sur place Exclu du prêt

Comprehensive Chirality. Vol.3 : Synthetic methods II – Chiral auxiliaries / Erick M. Carreira

Public ISBD Titre de série : Comprehensive Chirality Titre : Vol.3 : Synthetic methods II – Chiral auxiliaries Type de document : texte imprimé Auteurs : Erick M. Carreira, Éditeur scientifique ; Hisashi Yamamoto, Éditeur scientifique ; Robert K. Boeckman Jr., Éditeur scientifique Editeur : Amsterdam : Elsevier Année de publication : 2012 Collection : Comprehensive Chirality Importance : xxvi, 859 p. Format : 28 cm ISBN/ISSN/EAN : 978-0-08-095167-6 Langues : Anglais (eng) Note de contenu : "* Amino acid derived auxiliaries: Amino acids as chiral auxiliaries * Amino acid derived heterocyclic chiral auxiliaries: The use of oxazolidinones, oxazolidinethiones, thiazolidinethiones, and imidazolidinones * Terpene derived auxiliaries: Camphor and pinene derived auxiliaries * Terpene derived auxiliaries: Menthol and pulegone derived auxiliaries * Terpene derived auxiliaries: Miscellaneous terpene derived auxiliaries * Acetogenin (polypriopionate) derived auxiliaries: Tartaric acid * Acetogenin (polypriopionate) derived auxillaries: Hydroxyacids * Acetogenin (polypriopionate) derived auxillaries: Hydroxyacid derivatives * Alkaloid derived auxiliaries: Cinchona alkaloids and derivatives * Alkaloid-derived auxiliaries: Ephedra alkaloids * Alkaloid derived auxiliaries: Miscellaneous alkaloids * Carbohydrate derived auxiliaries: Mono (and disaccharide) derivatives * Carbohydrate derived auxiliaries: Amino sugar and glycosylamine auxiliaries * Synthetically derived chiral auxiliaries: Uses of derivatives of non-carbohydrate aldehydes and ketones in asymmetric synthesis * Non-chiral pool derived synthetic auxiliaries: Use of C2 -symmetric chiral diols * Synthetically derived auxiliaries: amines (including diamines), hydrazines and hydroxylamines, and amino alcohols * Synthetically derived auxiliaries: Phosphorus derivatives * Synthetically derived auxiliaries: Sulfur derivatives (including sulfilamines and sulfoximines) * Synthetically derived auxiliaries: Organometallic derivatives (main group and transition metals) * Stoichiometric auxiliary ligands for metals and main group elements: Ligands for lithium * Stoichiometric auxiliary ligands for metals and main group elements: Ligands for magnesium and calcium * Chiral ligation for boron and aluminum in stoichiometric asymmetric synthesis * Stoichiometric auxiliary ligands for metals and main group elements: Ligands for silicon * Stoichiometric auxiliary ligands for metals and main group elements: Ligands for tin and stannanes * Stoichiometric auxiliary ligands for metals and main group elements: Ligands for zinc * Stoichiometric auxiliary ligands for metals and main group elements: Ligands for chromium * Stoichiometric auxiliary ligands for metals and main group elements: Ligands for titanium and zirconium complexes." Cote : EXCLU (SdL) Num_Inv : 3292 Comprehensive Chirality. Vol.3 : Synthetic methods II – Chiral auxiliaries [texte imprimé] / Erick M. Carreira, Éditeur scientifique ; Hisashi Yamamoto, Éditeur scientifique ; Robert K. Boeckman Jr., Éditeur scientifique . - Amsterdam : Elsevier, 2012 . - xxvi, 859 p. ; 28 cm. - (Comprehensive Chirality) . ISBN : 978-0-08-095167-6 Langues : Anglais (eng) Note de contenu : "* Amino acid derived auxiliaries: Amino acids as chiral auxiliaries * Amino acid derived heterocyclic chiral auxiliaries: The use of oxazolidinones, oxazolidinethiones, thiazolidinethiones, and imidazolidinones * Terpene derived auxiliaries: Camphor and pinene derived auxiliaries * Terpene derived auxiliaries: Menthol and pulegone derived auxiliaries * Terpene derived auxiliaries: Miscellaneous terpene derived auxiliaries * Acetogenin (polypriopionate) derived auxiliaries: Tartaric acid * Acetogenin (polypriopionate) derived auxillaries: Hydroxyacids * Acetogenin (polypriopionate) derived auxillaries: Hydroxyacid derivatives * Alkaloid derived auxiliaries: Cinchona alkaloids and derivatives * Alkaloid-derived auxiliaries: Ephedra alkaloids * Alkaloid derived auxiliaries: Miscellaneous alkaloids * Carbohydrate derived auxiliaries: Mono (and disaccharide) derivatives * Carbohydrate derived auxiliaries: Amino sugar and glycosylamine auxiliaries * Synthetically derived chiral auxiliaries: Uses of derivatives of non-carbohydrate aldehydes and ketones in asymmetric synthesis * Non-chiral pool derived synthetic auxiliaries: Use of C2 -symmetric chiral diols * Synthetically derived auxiliaries: amines (including diamines), hydrazines and hydroxylamines, and amino alcohols * Synthetically derived auxiliaries: Phosphorus derivatives * Synthetically derived auxiliaries: Sulfur derivatives (including sulfilamines and sulfoximines) * Synthetically derived auxiliaries: Organometallic derivatives (main group and transition metals) * Stoichiometric auxiliary ligands for metals and main group elements: Ligands for lithium * Stoichiometric auxiliary ligands for metals and main group elements: Ligands for magnesium and calcium * Chiral ligation for boron and aluminum in stoichiometric asymmetric synthesis * Stoichiometric auxiliary ligands for metals and main group elements: Ligands for silicon * Stoichiometric auxiliary ligands for metals and main group elements: Ligands for tin and stannanes * Stoichiometric auxiliary ligands for metals and main group elements: Ligands for zinc * Stoichiometric auxiliary ligands for metals and main group elements: Ligands for chromium * Stoichiometric auxiliary ligands for metals and main group elements: Ligands for titanium and zirconium complexes." Cote : EXCLU (SdL) Num_Inv : 3292

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
3292	EXCLU	Texte imprimé	Salle de lecture	Encyclopédie	Consultation sur place Exclu du prêt

Comprehensive Chirality. Vol.4 : Synthetic methods III – Catalytic methods: C–C bond formation / Erick M. Carreira

Public ISBD Titre de série : Comprehensive Chirality Titre : Vol.4 : Synthetic methods III – Catalytic methods: C–C bond formation Type de document : texte imprimé Auteurs : Erick M. Carreira, Éditeur scientifique ; Hisashi Yamamoto, Éditeur scientifique ; Masakatsu Shibasaki, Éditeur scientifique Editeur : Amsterdam : Elsevier Année de publication : 2012 Collection : Comprehensive Chirality Importance : xxvi, 390 p. Format : 28 cm ISBN/ISSN/EAN : 978-0-08-095167-6 Langues : Anglais (eng) Note de contenu : "* Introduction: General concepts * C–C bond-forming reactions via the Heck reaction * C–C bond-forming reactions via cross-coupling * C–C bond formation (metathesis) * C–C bond formation by metal-catalyzed asymmetric allylic alkylation * C–C bond formation (metal-catalyzed reductive aldol coupling) * C–C bond formation (transition metal-catalyzed Michael) * C–C bond formation (metal-carbene catalyzed) * C–C bond formation using Lewis acids and silicon enolates * Enantioselective aldol reactions catalyzed by chiral Lewis bases * C–C bond-forming reactions via transmetallation using silyl enol ethers * Direct C–C bond formation (Henry, aza-Henry) * Direct C–C bond formation (Michael, aldol, and Mannich) * Reactions using thioamide and allylic cyanide * C–C bond formation * Enantioselective cyanation of carbonyls and imines * Asymmetric 1,2-addition of organometallics to carbonyl and imine groups * C–C bond formation (1,2-alkenylation) * To catalytic asymmetric 1,2-alkynylation * Other C–C bond formations including Au." Cote : EXCLU (SdL) Num_Inv : 3293 Comprehensive Chirality. Vol.4 : Synthetic methods III – Catalytic methods: C–C bond formation [texte imprimé] / Erick M. Carreira, Éditeur scientifique ; Hisashi Yamamoto, Éditeur scientifique ; Masakatsu Shibasaki, Éditeur scientifique . - Amsterdam : Elsevier, 2012 . - xxvi, 390 p. ; 28 cm. - (Comprehensive Chirality) . ISBN : 978-0-08-095167-6 Langues : Anglais (eng) Note de contenu : "* Introduction: General concepts * C–C bond-forming reactions via the Heck reaction * C–C bond-forming reactions via cross-coupling * C–C bond formation (metathesis) * C–C bond formation by metal-catalyzed asymmetric allylic alkylation * C–C bond formation (metal-catalyzed reductive aldol coupling) * C–C bond formation (transition metal-catalyzed Michael) * C–C bond formation (metal-carbene catalyzed) * C–C bond formation using Lewis acids and silicon enolates * Enantioselective aldol reactions catalyzed by chiral Lewis bases * C–C bond-forming reactions via transmetallation using silyl enol ethers * Direct C–C bond formation (Henry, aza-Henry) * Direct C–C bond formation (Michael, aldol, and Mannich) * Reactions using thioamide and allylic cyanide * C–C bond formation * Enantioselective cyanation of carbonyls and imines * Asymmetric 1,2-addition of organometallics to carbonyl and imine groups * C–C bond formation (1,2-alkenylation) * To catalytic asymmetric 1,2-alkynylation * Other C–C bond formations including Au." Cote : EXCLU (SdL) Num_Inv : 3293

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
3293	EXCLU	Texte imprimé	Salle de lecture	Encyclopédie	Consultation sur place Exclu du prêt

Comprehensive Chirality. Vol.5 : Synthetic methods IV – Asymmetric oxidation reduction, C–N / Erick M. Carreira

Public ISBD Titre de série : Comprehensive Chirality Titre : Vol.5 : Synthetic methods IV – Asymmetric oxidation reduction, C–N Type de document : texte imprimé Auteurs : Erick M. Carreira, Éditeur scientifique ; Hisashi Yamamoto, Éditeur scientifique ; Keiji Maruoka, Éditeur scientifique Editeur : Amsterdam : Elsevier Année de publication : 2012 Collection : Comprehensive Chirality Importance : xxvi, 599 p. Format : 28 cm ISBN/ISSN/EAN : 978-0-08-095167-6 Langues : Anglais (eng) Note de contenu : "* Asymmetric Baeyer–Villiger oxidation * Oxidation: C–O bond formation by C–H activation * Oxidation: Epoxidation (allylic alcohol, homoallylic alcohol, simple C=C, electron deficient C=C) * Oxidation: ?-hydroxylation of carbonyls * Oxidation: C–N bond formation by oxidation: C–H bond activation * Oxidation: C–N bond formation by oxidation (aziridines) * Oxidation: C–N bond formation by oxidation: Dinitrogen addition to double bond (diamino) * Asymmetric S–O bond formation by oxidation * Oxidation: C–X bond formation (X=Halogen, S, Se) * Reduction – hydrogenation: C=C; chemoselective * Reduction – hydrogenation: C=O; chemoselective * Asymmetric hydrogenation of prochiral C=N bonds * Reduction: Hydrosilylation * Reduction: Hydroformylation C–H and C–C * Reduction: Hydrocyanation of C=C * Reduction: Enantioselective hydrovinylation of alkenes * Reduction: Pinacol coupling * Addition reaction: Kinetic resolution * Addition reaction: 1,4 addition heteroatom * Addition reaction: Cycloaddition involving oxidation (N=N, N=O; No C–C bond formed) * Desymmetrization of meso diols * Desymmetrization of meso epoxide * Desymmetrization of meso anhydride." Cote : EXCLU (SdL) Num_Inv : 3294 Comprehensive Chirality. Vol.5 : Synthetic methods IV – Asymmetric oxidation reduction, C–N [texte imprimé] / Erick M. Carreira, Éditeur scientifique ; Hisashi Yamamoto, Éditeur scientifique ; Keiji Maruoka, Éditeur scientifique . - Amsterdam : Elsevier, 2012 . - xxvi, 599 p. ; 28 cm. - (Comprehensive Chirality) . ISBN : 978-0-08-095167-6 Langues : Anglais (eng) Note de contenu : "* Asymmetric Baeyer–Villiger oxidation * Oxidation: C–O bond formation by C–H activation * Oxidation: Epoxidation (allylic alcohol, homoallylic alcohol, simple C=C, electron deficient C=C) * Oxidation: ?-hydroxylation of carbonyls * Oxidation: C–N bond formation by oxidation: C–H bond activation * Oxidation: C–N bond formation by oxidation (aziridines) * Oxidation: C–N bond formation by oxidation: Dinitrogen addition to double bond (diamino) * Asymmetric S–O bond formation by oxidation * Oxidation: C–X bond formation (X=Halogen, S, Se) * Reduction – hydrogenation: C=C; chemoselective * Reduction – hydrogenation: C=O; chemoselective * Asymmetric hydrogenation of prochiral C=N bonds * Reduction: Hydrosilylation * Reduction: Hydroformylation C–H and C–C * Reduction: Hydrocyanation of C=C * Reduction: Enantioselective hydrovinylation of alkenes * Reduction: Pinacol coupling * Addition reaction: Kinetic resolution * Addition reaction: 1,4 addition heteroatom * Addition reaction: Cycloaddition involving oxidation (N=N, N=O; No C–C bond formed) * Desymmetrization of meso diols * Desymmetrization of meso epoxide * Desymmetrization of meso anhydride." Cote : EXCLU (SdL) Num_Inv : 3294

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
3294	EXCLU	Texte imprimé	Salle de lecture	Encyclopédie	Consultation sur place Exclu du prêt

Comprehensive Chirality. Vol.6 : Synthetic methods V – Organocatalysis / Erick M. Carreira

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Comprehensive Chirality. Vol.7 : Synthetic methods VI – Enzymatic and semi-enzymatic / Erick M. Carreira

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Comprehensive Chirality. Vol.8 : Separations and analysis / Erick M. Carreira

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Comprehensive Chirality. Vol.9 : Industrial applications of asymmetric synthesis / Erick M. Carreira

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