Titre :	Cisplatin: Chemistry and biochemistry of a leading anticancer drug
Type de document :	texte imprimé
Auteurs :	Bernhard Lippert, Éditeur scientifique
Editeur :	Zurich : Helvetica Chimica Acta
Année de publication :	1999
Autre Editeur :	Weinheim : Wiley-VCH
Importance :	xii, 563 p.
Format :	25 cm
ISBN/ISSN/EAN :	978-3-906390-20-8
Langues :	Anglais (eng)
Catégories :	Biochimie
Tags :	CISPLATIN  CANCER CHEMOTHERAPY
Index. décimale :	B-F
Résumé :	"30 years after its discovery as an antitumor agent, cisplatin represents today one of the most successful drugs in chemotherapy. This book is intended to reminisce this event, to take inventory, and to point out new lines of development in this field. Divided in 6 sections and 22 chapters, the book provides an up-to-date account on topics such as * the chemistry and biochemistry of cisplatin, * the clinical status of Pt anticancer drugs, * the impact of cisplatin on inorganic and coordination chemistry, * new developments in drug design, testing and delivery. It also includes a chapter describing the historical development of the discovery of cisplatin. The ultimate question - How does cisplatin kill a cell? - is yet to be answered, but there are now new links suggesting how Pt binding to DNA may trigger a cascade of cellular reactions that eventually result in apoptosis[...]."
Cote :	B-F030 (SdS)
Num_Inv :	2441

Cisplatin: Chemistry and biochemistry of a leading anticancer drug [texte imprimé] / Bernhard Lippert, Éditeur scientifique . - Zurich : Helvetica Chimica Acta : Weinheim : Wiley-VCH, 1999 . - xii, 563 p. ; 25 cm.
ISBN : 978-3-906390-20-8
Langues : Anglais (eng)

Catégories :	Biochimie
Tags :	CISPLATIN  CANCER CHEMOTHERAPY
Index. décimale :	B-F
Résumé :	"30 years after its discovery as an antitumor agent, cisplatin represents today one of the most successful drugs in chemotherapy. This book is intended to reminisce this event, to take inventory, and to point out new lines of development in this field. Divided in 6 sections and 22 chapters, the book provides an up-to-date account on topics such as * the chemistry and biochemistry of cisplatin, * the clinical status of Pt anticancer drugs, * the impact of cisplatin on inorganic and coordination chemistry, * new developments in drug design, testing and delivery. It also includes a chapter describing the historical development of the discovery of cisplatin. The ultimate question - How does cisplatin kill a cell? - is yet to be answered, but there are now new links suggesting how Pt binding to DNA may trigger a cascade of cellular reactions that eventually result in apoptosis[...]."
Cote :	B-F030 (SdS)
Num_Inv :	2441