Titre : |
Organometallic chemistry in industry: A practical approach |
Type de document : |
texte imprimé |
Auteurs : |
Thomas J. Colacot, Éditeur scientifique ; Carin C. C. Johansson Seechurn, Éditeur scientifique ; Robert H. Grubbs, Éditeur scientifique |
Editeur : |
Weinheim : Wiley-VCH |
Année de publication : |
2020 |
Importance : |
xix, 315 p. |
ISBN/ISSN/EAN : |
978-3-527-34517-5 |
Langues : |
Anglais (eng) |
Catégories : |
Généralités en Chimie
|
Tags : |
ORGANOMETALLIC CHEMISTRY ORGANOMETALLIC CHEMISTRY--Industrial applications |
Index. décimale : |
B-A |
Résumé : |
"This comprehensive book takes a practical approach to how organometallic chemistry is being used in industrial applications. It uniquely offers numerous, real-world examples and case studies that aid working R&D researchers as well as Ph.D. and postdoc students preparing to ace interviews in order to enter the workforce. Edited by two world-leading and established industrial chemists, the book covers flow chemistry (catalytic and non-catalytic organometallic chemistry), various cross-coupling reactions (C-C, C-N, and C-B) in classical batch chemistry, conjugate addition reactions, metathesis, and C-H arylation and achiral hydrogenation reactions.
Beginning with an overview of the many industrial milestones within the field over the years, Organometallic Chemistry in Industry: A Practical Approach provides chapters covering: the design, development, and execution of a continuous flow enabled API manufacturing route; continuous manufacturing as an enabling technology for low temperature organometallic chemistry; the development of a nickel-catalyzed enantioselective Mizoroki-Heck coupling; and the development of iron-catalyzed Kumada cross-coupling for the large scale production of Aliskiren intermediates. The book also examines aspects of homogeneous hydrogenation from industrial research; the latest industrial uses of olefin metathesis; and more." |
Note de contenu : |
"* Industrial Milestones in Organometallic Chemistry
* Design, Development, and Execution of a Continuous-flow-Enabled API Manufacturing Route
* Continuous Manufacturing as an Enabling Technology for Low-Temperature Organometallic Chemistry
* Development of a Nickel-Catalyzed Enantioselective Mizoroki–Heck Coupling
* Development of Iron-Catalyzed Kumada Cross-coupling for the Large-Scale Production of Aliskiren Intermediate
* Development and Scale-Up of a Palladium-Catalyzed Intramolecular Direct Arylation in the Commercial Synthesis of Beclabuvir
* Ruthenium-Catalyzed C—H Activated C—C/N/O Bond Formation Reactions for the Practical Synthesis of Heterocycles and Pharmaceutical Agents
* Cross-couplings in Water – A Better Way to Assemble New Bonds
* Aspects of Homogeneous Hydrogenation from Industrial Research
* Latest Industrial Uses of Olefin Metathesis
* Dehydrative Decarbonylation" |
Cote : |
B-A098 |
Num_Inv : |
00106 |
Localisation : |
LCC (SdS) |
Organometallic chemistry in industry: A practical approach [texte imprimé] / Thomas J. Colacot, Éditeur scientifique ; Carin C. C. Johansson Seechurn, Éditeur scientifique ; Robert H. Grubbs, Éditeur scientifique . - Weinheim : Wiley-VCH, 2020 . - xix, 315 p. ISBN : 978-3-527-34517-5 Langues : Anglais ( eng)
Catégories : |
Généralités en Chimie
|
Tags : |
ORGANOMETALLIC CHEMISTRY ORGANOMETALLIC CHEMISTRY--Industrial applications |
Index. décimale : |
B-A |
Résumé : |
"This comprehensive book takes a practical approach to how organometallic chemistry is being used in industrial applications. It uniquely offers numerous, real-world examples and case studies that aid working R&D researchers as well as Ph.D. and postdoc students preparing to ace interviews in order to enter the workforce. Edited by two world-leading and established industrial chemists, the book covers flow chemistry (catalytic and non-catalytic organometallic chemistry), various cross-coupling reactions (C-C, C-N, and C-B) in classical batch chemistry, conjugate addition reactions, metathesis, and C-H arylation and achiral hydrogenation reactions.
Beginning with an overview of the many industrial milestones within the field over the years, Organometallic Chemistry in Industry: A Practical Approach provides chapters covering: the design, development, and execution of a continuous flow enabled API manufacturing route; continuous manufacturing as an enabling technology for low temperature organometallic chemistry; the development of a nickel-catalyzed enantioselective Mizoroki-Heck coupling; and the development of iron-catalyzed Kumada cross-coupling for the large scale production of Aliskiren intermediates. The book also examines aspects of homogeneous hydrogenation from industrial research; the latest industrial uses of olefin metathesis; and more." |
Note de contenu : |
"* Industrial Milestones in Organometallic Chemistry
* Design, Development, and Execution of a Continuous-flow-Enabled API Manufacturing Route
* Continuous Manufacturing as an Enabling Technology for Low-Temperature Organometallic Chemistry
* Development of a Nickel-Catalyzed Enantioselective Mizoroki–Heck Coupling
* Development of Iron-Catalyzed Kumada Cross-coupling for the Large-Scale Production of Aliskiren Intermediate
* Development and Scale-Up of a Palladium-Catalyzed Intramolecular Direct Arylation in the Commercial Synthesis of Beclabuvir
* Ruthenium-Catalyzed C—H Activated C—C/N/O Bond Formation Reactions for the Practical Synthesis of Heterocycles and Pharmaceutical Agents
* Cross-couplings in Water – A Better Way to Assemble New Bonds
* Aspects of Homogeneous Hydrogenation from Industrial Research
* Latest Industrial Uses of Olefin Metathesis
* Dehydrative Decarbonylation" |
Cote : |
B-A098 |
Num_Inv : |
00106 |
Localisation : |
LCC (SdS) |
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