Titre :	Organometallic chemistry in industry: a practical approach : A practical approach
Type de document :	texte imprimé
Auteurs :	Colacot, Thomas J., Éditeur scientifique ; Johansson Seechurn, Carin C. C., Éditeur scientifique ; Grubbs, Robert H., Éditeur scientifique
Editeur :	New York : Wiley
Année de publication :	2020
Importance :	xvii, 336 p.
ISBN/ISSN/EAN :	978-3-527-34517-5
Langues :	Anglais (eng)
Catégories :	Chimie : Généralités ; Technologies, Méthodes, Réactions
Tags :	CHEMISTRY-INDUSTRIAL APPLICATIONS  ORGANOMETALLIC CHEMISTRY
Index. décimale :	B-A
Résumé :	This comprehensive book takes a practical approach to how organometallic chemistry is being used in industrial applications. It uniquely offers numerous, real-world examples and case studies that aid working R&D researchers as well as Ph.D. and postdoc students preparing to ace interviews in order to enter the workforce. Edited by two world-leading and established industrial chemists, the book covers flow chemistry (catalytic and non-catalytic organometallic chemistry), various cross-coupling reactions (C-C, C-N, and C-B) in classical batch chemistry, conjugate addition reactions, metathesis, and C-H arylation and achiral hydrogenation reactions. Beginning with an overview of the many industrial milestones within the field over the years, Organometallic Chemistry in Industry: A Practical Approach provides chapters covering: the design, development, and execution of a continuous flow enabled API manufacturing route; continuous manufacturing as an enabling technology for low temperature organometallic chemistry; the development of a nickel-catalyzed enantioselective Mizoroki-Heck coupling; and the development of iron-catalyzed Kumada cross-coupling for the large scale production of Aliskiren intermediates. The book also examines aspects of homogeneous hydrogenation from industrial research; the latest industrial uses of olefin metathesis; and more.
Note de contenu :	"* Industrial Milestones in Organometallic Chemistry * Design, Development, and Execution of a Continuous-flow-Enabled API Manufacturing Route * Continuous Manufacturing as an Enabling Technology for Low-Temperature Organometallic Chemistry * Development of a Nickel-Catalyzed Enantioselective Mizoroki–Heck Coupling * Development of Iron-Catalyzed Kumada Cross-coupling for the Large-Scale Production of Aliskiren Intermediate * Development and Scale-Up of a Palladium-Catalyzed Intramolecular Direct Arylation in the Commercial Synthesis of Beclabuvir * Ruthenium-Catalyzed C—H Activated C—C/N/O Bond Formation Reactions for the Practical Synthesis of Heterocycles and Pharmaceutical Agents * Cross-couplings in Water – A Better Way to Assemble New Bonds * Aspects of Homogeneous Hydrogenation from Industrial Research * Latest Industrial Uses of Olefin Metathesis * Dehydrative Decarbonylation".
Cote :	B-A124
Num_Inv :	738
Localisation :	LCC (SdS)

Organometallic chemistry in industry: a practical approach : A practical approach [texte imprimé] / Colacot, Thomas J., Éditeur scientifique ; Johansson Seechurn, Carin C. C., Éditeur scientifique ; Grubbs, Robert H., Éditeur scientifique . - New York : Wiley, 2020 . - xvii, 336 p.
ISBN : 978-3-527-34517-5
Langues : Anglais (eng)

Catégories :	Chimie : Généralités ; Technologies, Méthodes, Réactions
Tags :	CHEMISTRY-INDUSTRIAL APPLICATIONS  ORGANOMETALLIC CHEMISTRY
Index. décimale :	B-A
Résumé :	This comprehensive book takes a practical approach to how organometallic chemistry is being used in industrial applications. It uniquely offers numerous, real-world examples and case studies that aid working R&D researchers as well as Ph.D. and postdoc students preparing to ace interviews in order to enter the workforce. Edited by two world-leading and established industrial chemists, the book covers flow chemistry (catalytic and non-catalytic organometallic chemistry), various cross-coupling reactions (C-C, C-N, and C-B) in classical batch chemistry, conjugate addition reactions, metathesis, and C-H arylation and achiral hydrogenation reactions. Beginning with an overview of the many industrial milestones within the field over the years, Organometallic Chemistry in Industry: A Practical Approach provides chapters covering: the design, development, and execution of a continuous flow enabled API manufacturing route; continuous manufacturing as an enabling technology for low temperature organometallic chemistry; the development of a nickel-catalyzed enantioselective Mizoroki-Heck coupling; and the development of iron-catalyzed Kumada cross-coupling for the large scale production of Aliskiren intermediates. The book also examines aspects of homogeneous hydrogenation from industrial research; the latest industrial uses of olefin metathesis; and more.
Note de contenu :	"* Industrial Milestones in Organometallic Chemistry * Design, Development, and Execution of a Continuous-flow-Enabled API Manufacturing Route * Continuous Manufacturing as an Enabling Technology for Low-Temperature Organometallic Chemistry * Development of a Nickel-Catalyzed Enantioselective Mizoroki–Heck Coupling * Development of Iron-Catalyzed Kumada Cross-coupling for the Large-Scale Production of Aliskiren Intermediate * Development and Scale-Up of a Palladium-Catalyzed Intramolecular Direct Arylation in the Commercial Synthesis of Beclabuvir * Ruthenium-Catalyzed C—H Activated C—C/N/O Bond Formation Reactions for the Practical Synthesis of Heterocycles and Pharmaceutical Agents * Cross-couplings in Water – A Better Way to Assemble New Bonds * Aspects of Homogeneous Hydrogenation from Industrial Research * Latest Industrial Uses of Olefin Metathesis * Dehydrative Decarbonylation".
Cote :	B-A124
Num_Inv :	738
Localisation :	LCC (SdS)