Active pharmaceutical ingredients in synthesis / Burke, A. J.

Public ISBD Titre : Active pharmaceutical ingredients in synthesis : Catalytic processes in research and development Type de document : texte imprimé Auteurs : Burke, A. J., Éditeur scientifique ; Marques, C. S., Éditeur scientifique ; Nicholas J. Turner, Éditeur scientifique ; Hermann, Gesine J., Éditeur scientifique Editeur : Wiley-VCH Verlag Année de publication : 2018 Importance : xxiii, 426 p. ISBN/ISSN/EAN : 978-3-527-34241-9 Langues : Anglais (eng) Catégories : Catalyse Tags : CATALYSIS  CATALYSIS-INDUSTRIAL APPLICATIONS  ENANTIOMER  ENANTIOSELECTIVE CATALYSIS  ENANTIOSELECTIVE CATALYSIS-INDUSTRIAL APPLICATIONS  PHARMACEUTICAL CHEMISTRY Index. décimale : B-E Résumé : Presents the most effective catalytic reactions in use today, with a special focus on process intensification, sustainability, waste reduction, and innovative methods This book demonstrates the importance of efficient catalytic transformations for producing pharmaceutically active molecules. It presents the key catalytic reactions and the most efficient catalytic processes, including their significant advantages over compared previous methods. It also places a strong emphasis on asymmetric catalytic reactions, process intensification (PI), sustainability and waste mitigation, continuous manufacturing processes as enshrined by continuous flow catalysis, and supported catalysis. Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development offers chapters covering: Catalysis and Prerequisites for the Modern Pharmaceutial Industry Landscape; Catalytic Process Design - The Industrial Perspective; Hydrogenation, Hydroformylation and Other Reductions; Oxidation; ; Catalytic Addition Reactions; Catalytic Cross-Coupling Reactions; Catalytic Metathesis Reactions; Catalytic Cycloaddition Reactions: Coming Full-Circle; Catalytic Cyclopropanation Reactions; Catalytic C-H insertion Reactions; Phase Transfer Catalysis; and Biocatalysis. -Provides the reader with an updated clear view of the current state of the challenging field of catalysis for API production -Focuses on the application of catalytic methods for the synthesis of known APIs -Presents every key reaction, including Diels-Alder, CH Insertions, Metal-catalytic coupling-reactions, and many more -Includes recent patent literature for completeness Covering a topic of great interest for synthetic chemists and R&D researchers in the pharmaceutical industry, Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development is a must-read for every synthetic chemist working with APIs. Note de contenu : *" Catalysis and Prerequisites for the Modern Pharmaceutical Industry Landscape * Catalytic Process Design: The Industrial Perspective * Hydrogenation, Hydroformylation, and Other Reductions * Oxidation: Nobel Prize Chemistry Catalysis * Catalytic Addition Reactions * Catalytic Cross?Coupling Reactions – Nobel Prize Catalysis * Catalytic Metathesis Reactions: Nobel Prize Catalysis * Catalytic Cycloaddition Reactions: Coming Full Circle * Catalytic Cyclopropanation Reactions * Catalytic C–H Insertion Reactions * Phase?Transfer Catalysis * Biocatalysis". Cote : B-E092 Num_Inv : 3544 Localisation : LCC (SdS) Active pharmaceutical ingredients in synthesis : Catalytic processes in research and development [texte imprimé] / Burke, A. J., Éditeur scientifique ; Marques, C. S., Éditeur scientifique ; Nicholas J. Turner, Éditeur scientifique ; Hermann, Gesine J., Éditeur scientifique . - Wiley-VCH Verlag, 2018 . - xxiii, 426 p. ISBN : 978-3-527-34241-9 Langues : Anglais (eng) Catégories : Catalyse Tags : CATALYSIS  CATALYSIS-INDUSTRIAL APPLICATIONS  ENANTIOMER  ENANTIOSELECTIVE CATALYSIS  ENANTIOSELECTIVE CATALYSIS-INDUSTRIAL APPLICATIONS  PHARMACEUTICAL CHEMISTRY Index. décimale : B-E Résumé : Presents the most effective catalytic reactions in use today, with a special focus on process intensification, sustainability, waste reduction, and innovative methods This book demonstrates the importance of efficient catalytic transformations for producing pharmaceutically active molecules. It presents the key catalytic reactions and the most efficient catalytic processes, including their significant advantages over compared previous methods. It also places a strong emphasis on asymmetric catalytic reactions, process intensification (PI), sustainability and waste mitigation, continuous manufacturing processes as enshrined by continuous flow catalysis, and supported catalysis. Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development offers chapters covering: Catalysis and Prerequisites for the Modern Pharmaceutial Industry Landscape; Catalytic Process Design - The Industrial Perspective; Hydrogenation, Hydroformylation and Other Reductions; Oxidation; ; Catalytic Addition Reactions; Catalytic Cross-Coupling Reactions; Catalytic Metathesis Reactions; Catalytic Cycloaddition Reactions: Coming Full-Circle; Catalytic Cyclopropanation Reactions; Catalytic C-H insertion Reactions; Phase Transfer Catalysis; and Biocatalysis. -Provides the reader with an updated clear view of the current state of the challenging field of catalysis for API production -Focuses on the application of catalytic methods for the synthesis of known APIs -Presents every key reaction, including Diels-Alder, CH Insertions, Metal-catalytic coupling-reactions, and many more -Includes recent patent literature for completeness Covering a topic of great interest for synthetic chemists and R&D researchers in the pharmaceutical industry, Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development is a must-read for every synthetic chemist working with APIs. Note de contenu : *" Catalysis and Prerequisites for the Modern Pharmaceutical Industry Landscape * Catalytic Process Design: The Industrial Perspective * Hydrogenation, Hydroformylation, and Other Reductions * Oxidation: Nobel Prize Chemistry Catalysis * Catalytic Addition Reactions * Catalytic Cross?Coupling Reactions – Nobel Prize Catalysis * Catalytic Metathesis Reactions: Nobel Prize Catalysis * Catalytic Cycloaddition Reactions: Coming Full Circle * Catalytic Cyclopropanation Reactions * Catalytic C–H Insertion Reactions * Phase?Transfer Catalysis * Biocatalysis". Cote : B-E092 Num_Inv : 3544 Localisation : LCC (SdS)

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
3544	B-E092	Texte imprimé	Bibliothèque	Livre	Disponible

Comprehensive Chirality. Vol.7 : Synthetic methods VI – Enzymatic and semi-enzymatic / Erick M. Carreira

Public ISBD Titre de série : Comprehensive Chirality Titre : Vol.7 : Synthetic methods VI – Enzymatic and semi-enzymatic Type de document : texte imprimé Auteurs : Erick M. Carreira, Éditeur scientifique ; Hisashi Yamamoto, Éditeur scientifique ; Nicholas J. Turner, Éditeur scientifique Editeur : Amsterdam : Elsevier Année de publication : 2012 Collection : Comprehensive Chirality Importance : xxvi, 552 p. Format : 28 cm ISBN/ISSN/EAN : 978-0-08-095167-6 Langues : Anglais (eng) Note de contenu : "* Introduction and general concepts * Screening methods for enzymes * Directed evolution and (semi-) rational design strategies for the creation of synthetically useful, stereoselective biocatalysts * Cofactor recycling for enzyme catalyzed processes * Reaction engineering of biotransformations * Hydrolysis and reverse hydrolysis: Hydrolysis and formation of amides * Hydrolysis and reverse hydrolysis: Selective nitrile hydrolysis using nitrilase and its related enzymes * Hydrolysis and reverse hydrolysis: Halohydrin dehalogenases * Hydrolysis and reverse hydrolysis: Dynamic kinetic resolution * Reduction: Asymmetric biocatalytic reduction of ketones * Reduction: Enantioselective bioreduction of C–C double bonds * Oxidation: Oxidases * Oxidation: Stereoselective oxidations with cytochrome P450 monooxygenases * Oxidation: Asymmetric enzymatic sulfoxidation * Oxidation: Haloperoxidases * C–X bond formation: Hydroxynitrile lyases: From nature to application * C–X bond formation: C–C bond formation using TDP-dependent enzymes * C–X bond formation: Transaminases as chiral catalysts: Mechanism, engineering, and applications * C–X bond formation: Enzymatic enantioselective decarboxylative protonation and C–C bond formation * Multi-enzyme reactions * Enzymatic carbohydrate synthesis * Enzyme catalytic promiscuity: Expanding the catalytic action of enzymes to new reactions * New emerging reactions * Enantioselective hybrid catalysts." Cote : EXCLU (SdL) Num_Inv : 3296 Comprehensive Chirality. Vol.7 : Synthetic methods VI – Enzymatic and semi-enzymatic [texte imprimé] / Erick M. Carreira, Éditeur scientifique ; Hisashi Yamamoto, Éditeur scientifique ; Nicholas J. Turner, Éditeur scientifique . - Amsterdam : Elsevier, 2012 . - xxvi, 552 p. ; 28 cm. - (Comprehensive Chirality) . ISBN : 978-0-08-095167-6 Langues : Anglais (eng) Note de contenu : "* Introduction and general concepts * Screening methods for enzymes * Directed evolution and (semi-) rational design strategies for the creation of synthetically useful, stereoselective biocatalysts * Cofactor recycling for enzyme catalyzed processes * Reaction engineering of biotransformations * Hydrolysis and reverse hydrolysis: Hydrolysis and formation of amides * Hydrolysis and reverse hydrolysis: Selective nitrile hydrolysis using nitrilase and its related enzymes * Hydrolysis and reverse hydrolysis: Halohydrin dehalogenases * Hydrolysis and reverse hydrolysis: Dynamic kinetic resolution * Reduction: Asymmetric biocatalytic reduction of ketones * Reduction: Enantioselective bioreduction of C–C double bonds * Oxidation: Oxidases * Oxidation: Stereoselective oxidations with cytochrome P450 monooxygenases * Oxidation: Asymmetric enzymatic sulfoxidation * Oxidation: Haloperoxidases * C–X bond formation: Hydroxynitrile lyases: From nature to application * C–X bond formation: C–C bond formation using TDP-dependent enzymes * C–X bond formation: Transaminases as chiral catalysts: Mechanism, engineering, and applications * C–X bond formation: Enzymatic enantioselective decarboxylative protonation and C–C bond formation * Multi-enzyme reactions * Enzymatic carbohydrate synthesis * Enzyme catalytic promiscuity: Expanding the catalytic action of enzymes to new reactions * New emerging reactions * Enantioselective hybrid catalysts." Cote : EXCLU (SdL) Num_Inv : 3296

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
3296	EXCLU	Texte imprimé	Salle de lecture	Encyclopédie	Consultation sur place Exclu du prêt

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