10 recherche sur le tag 'PHARMACEUTICAL CHEMISTRY'   

Active pharmaceutical ingredients in synthesis / Burke, A. J.

Public ISBD Titre : Active pharmaceutical ingredients in synthesis : Catalytic processes in research and development Type de document : texte imprimé Auteurs : Burke, A. J., Éditeur scientifique ; Marques, C. S., Éditeur scientifique ; Nicholas J. Turner, Éditeur scientifique ; Hermann, Gesine J., Éditeur scientifique Editeur : Wiley-VCH Verlag Année de publication : 2018 Importance : xxiii, 426 p. ISBN/ISSN/EAN : 978-3-527-34241-9 Langues : Anglais (eng) Catégories : Catalyse Tags : CATALYSIS  CATALYSIS-INDUSTRIAL APPLICATIONS  ENANTIOMER  ENANTIOSELECTIVE CATALYSIS  ENANTIOSELECTIVE CATALYSIS-INDUSTRIAL APPLICATIONS  PHARMACEUTICAL CHEMISTRY Index. décimale : B-E Résumé : Presents the most effective catalytic reactions in use today, with a special focus on process intensification, sustainability, waste reduction, and innovative methods This book demonstrates the importance of efficient catalytic transformations for producing pharmaceutically active molecules. It presents the key catalytic reactions and the most efficient catalytic processes, including their significant advantages over compared previous methods. It also places a strong emphasis on asymmetric catalytic reactions, process intensification (PI), sustainability and waste mitigation, continuous manufacturing processes as enshrined by continuous flow catalysis, and supported catalysis. Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development offers chapters covering: Catalysis and Prerequisites for the Modern Pharmaceutial Industry Landscape; Catalytic Process Design - The Industrial Perspective; Hydrogenation, Hydroformylation and Other Reductions; Oxidation; ; Catalytic Addition Reactions; Catalytic Cross-Coupling Reactions; Catalytic Metathesis Reactions; Catalytic Cycloaddition Reactions: Coming Full-Circle; Catalytic Cyclopropanation Reactions; Catalytic C-H insertion Reactions; Phase Transfer Catalysis; and Biocatalysis. -Provides the reader with an updated clear view of the current state of the challenging field of catalysis for API production -Focuses on the application of catalytic methods for the synthesis of known APIs -Presents every key reaction, including Diels-Alder, CH Insertions, Metal-catalytic coupling-reactions, and many more -Includes recent patent literature for completeness Covering a topic of great interest for synthetic chemists and R&D researchers in the pharmaceutical industry, Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development is a must-read for every synthetic chemist working with APIs. Note de contenu : *" Catalysis and Prerequisites for the Modern Pharmaceutical Industry Landscape * Catalytic Process Design: The Industrial Perspective * Hydrogenation, Hydroformylation, and Other Reductions * Oxidation: Nobel Prize Chemistry Catalysis * Catalytic Addition Reactions * Catalytic Cross?Coupling Reactions – Nobel Prize Catalysis * Catalytic Metathesis Reactions: Nobel Prize Catalysis * Catalytic Cycloaddition Reactions: Coming Full Circle * Catalytic Cyclopropanation Reactions * Catalytic C–H Insertion Reactions * Phase?Transfer Catalysis * Biocatalysis". Cote : B-E092 Num_Inv : 3544 Localisation : LCC (SdS) Active pharmaceutical ingredients in synthesis : Catalytic processes in research and development [texte imprimé] / Burke, A. J., Éditeur scientifique ; Marques, C. S., Éditeur scientifique ; Nicholas J. Turner, Éditeur scientifique ; Hermann, Gesine J., Éditeur scientifique . - Wiley-VCH Verlag, 2018 . - xxiii, 426 p. ISBN : 978-3-527-34241-9 Langues : Anglais (eng) Catégories : Catalyse Tags : CATALYSIS  CATALYSIS-INDUSTRIAL APPLICATIONS  ENANTIOMER  ENANTIOSELECTIVE CATALYSIS  ENANTIOSELECTIVE CATALYSIS-INDUSTRIAL APPLICATIONS  PHARMACEUTICAL CHEMISTRY Index. décimale : B-E Résumé : Presents the most effective catalytic reactions in use today, with a special focus on process intensification, sustainability, waste reduction, and innovative methods This book demonstrates the importance of efficient catalytic transformations for producing pharmaceutically active molecules. It presents the key catalytic reactions and the most efficient catalytic processes, including their significant advantages over compared previous methods. It also places a strong emphasis on asymmetric catalytic reactions, process intensification (PI), sustainability and waste mitigation, continuous manufacturing processes as enshrined by continuous flow catalysis, and supported catalysis. Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development offers chapters covering: Catalysis and Prerequisites for the Modern Pharmaceutial Industry Landscape; Catalytic Process Design - The Industrial Perspective; Hydrogenation, Hydroformylation and Other Reductions; Oxidation; ; Catalytic Addition Reactions; Catalytic Cross-Coupling Reactions; Catalytic Metathesis Reactions; Catalytic Cycloaddition Reactions: Coming Full-Circle; Catalytic Cyclopropanation Reactions; Catalytic C-H insertion Reactions; Phase Transfer Catalysis; and Biocatalysis. -Provides the reader with an updated clear view of the current state of the challenging field of catalysis for API production -Focuses on the application of catalytic methods for the synthesis of known APIs -Presents every key reaction, including Diels-Alder, CH Insertions, Metal-catalytic coupling-reactions, and many more -Includes recent patent literature for completeness Covering a topic of great interest for synthetic chemists and R&D researchers in the pharmaceutical industry, Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development is a must-read for every synthetic chemist working with APIs. Note de contenu : *" Catalysis and Prerequisites for the Modern Pharmaceutical Industry Landscape * Catalytic Process Design: The Industrial Perspective * Hydrogenation, Hydroformylation, and Other Reductions * Oxidation: Nobel Prize Chemistry Catalysis * Catalytic Addition Reactions * Catalytic Cross?Coupling Reactions – Nobel Prize Catalysis * Catalytic Metathesis Reactions: Nobel Prize Catalysis * Catalytic Cycloaddition Reactions: Coming Full Circle * Catalytic Cyclopropanation Reactions * Catalytic C–H Insertion Reactions * Phase?Transfer Catalysis * Biocatalysis". Cote : B-E092 Num_Inv : 3544 Localisation : LCC (SdS)

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
3544	B-E092	Texte imprimé	Bibliothèque	Livre	Disponible

Fluorine in medicinal chemistry and chemical biology / Iwao Ojima

Public ISBD Titre : Fluorine in medicinal chemistry and chemical biology Type de document : texte imprimé Auteurs : Iwao Ojima, Éditeur scientifique Editeur : Oxford : Wiley-Blackwell Année de publication : 2009 Importance : xvi, 624 p. Format : 26 cm ISBN/ISSN/EAN : 978-1-4051-6720-8 Langues : Anglais (eng) Catégories : Biochimie Tags : ORGANOFLUORINE COMPOUNDS  FLUORINE  BIOORGANIC CHEMISTRY  PHARMACEUTICAL CHEMISTRY Index. décimale : B-F Résumé : "The extraordinary potential of fluorine-containing molecules in medicinal chemistry and chemical biology has been recognized by researchers outside of the traditional fluorine chemistry field, and thus a new wave of fluorine chemistry is rapidly expanding its biomedical frontiers. With several of the best selling drugs in the world crucially containing fluorine atoms, the incorporation of fluorine to drug leads has become an essential practice in biomedical research, especially for drug design and discovery as well as development. Focusing on the unique and significant roles that fluorine plays in medicinal chemistry and chemical biology, this book reviews recent advances and future prospects in this rapidly developing field. Topics covered include: * Discovery and development of fluorine containing drugs and drug candidates. * New and efficient synthetic methods for medicinal chemistry and the optimisation of fluorine-containing drug candidates. * Structural and chemical biology of fluorinated amino acids and peptides. * Fluorine labels as probes in metabolic study, protein engineering and clinical diagnosis. * Applications of 19F NMR spectroscopy in biomedical research. An appendix presents an invaluable index of all fluorine-containing drugs that have been approved by the US Food and Drug Administration, including information on structure and pharmaceutical action. Fluorine in Medicinal Chemistry and Chemical Biology will serve as an excellent reference source for graduate students as well as academic and industrial researchers who want to take advantage of fluorine in biomedical research." Cote : B-F032 (SdS) Num_Inv : 2894 Fluorine in medicinal chemistry and chemical biology [texte imprimé] / Iwao Ojima, Éditeur scientifique . - Oxford : Wiley-Blackwell, 2009 . - xvi, 624 p. ; 26 cm. ISBN : 978-1-4051-6720-8 Langues : Anglais (eng) Catégories : Biochimie Tags : ORGANOFLUORINE COMPOUNDS  FLUORINE  BIOORGANIC CHEMISTRY  PHARMACEUTICAL CHEMISTRY Index. décimale : B-F Résumé : "The extraordinary potential of fluorine-containing molecules in medicinal chemistry and chemical biology has been recognized by researchers outside of the traditional fluorine chemistry field, and thus a new wave of fluorine chemistry is rapidly expanding its biomedical frontiers. With several of the best selling drugs in the world crucially containing fluorine atoms, the incorporation of fluorine to drug leads has become an essential practice in biomedical research, especially for drug design and discovery as well as development. Focusing on the unique and significant roles that fluorine plays in medicinal chemistry and chemical biology, this book reviews recent advances and future prospects in this rapidly developing field. Topics covered include: * Discovery and development of fluorine containing drugs and drug candidates. * New and efficient synthetic methods for medicinal chemistry and the optimisation of fluorine-containing drug candidates. * Structural and chemical biology of fluorinated amino acids and peptides. * Fluorine labels as probes in metabolic study, protein engineering and clinical diagnosis. * Applications of 19F NMR spectroscopy in biomedical research. An appendix presents an invaluable index of all fluorine-containing drugs that have been approved by the US Food and Drug Administration, including information on structure and pharmaceutical action. Fluorine in Medicinal Chemistry and Chemical Biology will serve as an excellent reference source for graduate students as well as academic and industrial researchers who want to take advantage of fluorine in biomedical research." Cote : B-F032 (SdS) Num_Inv : 2894

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
2894	B-F032	Texte imprimé	Bibliothèque	Livre	Disponible

Foye's principles of medicinal chemistry / David A. Williams

Public ISBD Titre : Foye's principles of medicinal chemistry Type de document : texte imprimé Auteurs : David A. Williams ; William O. Foye ; Thomas L. Lemke Mention d'édition : Fifth edition Editeur : Philadelphia : Lippincott Williams & Wilkins Année de publication : 2002 Importance : 1114 p. ISBN/ISSN/EAN : 978-0-683-30737-5 Langues : Anglais (eng) Tags : PHARMACEUTICAL CHEMISTRY Index. décimale : EQ -Equipe- Résumé : "This comprehensive Fifth Edition has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. The new emphasis is on pharmaceutical care that focuses on the patient, and on the pharmacist a therapeutic clinical consultant, rather than chemist. Approximately 45 contributors, respected in the field of pharmacy education, augment this exhaustive reference. New to this edition are chapters with standardized formats and features, such as Case Studies, Therapeutic Actions, Drug Interactions, and more." Cote : LCC/M Num_Inv : 2831 Foye's principles of medicinal chemistry [texte imprimé] / David A. Williams ; William O. Foye ; Thomas L. Lemke  . -  Fifth edition . - Philadelphia : Lippincott Williams & Wilkins, 2002 . - 1114 p. ISBN : 978-0-683-30737-5 Langues : Anglais (eng) Tags : PHARMACEUTICAL CHEMISTRY Index. décimale : EQ -Equipe- Résumé : "This comprehensive Fifth Edition has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. The new emphasis is on pharmaceutical care that focuses on the patient, and on the pharmacist a therapeutic clinical consultant, rather than chemist. Approximately 45 contributors, respected in the field of pharmacy education, augment this exhaustive reference. New to this edition are chapters with standardized formats and features, such as Case Studies, Therapeutic Actions, Drug Interactions, and more." Cote : LCC/M Num_Inv : 2831

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
2831	LCC/M	Texte imprimé	Equipe	Livre	Equipe - Demande préalable Disponible

Medicinal chemistry: An introduction / Garry Thomas

Public ISBD Titre : Medicinal chemistry: An introduction Type de document : texte imprimé Auteurs : Garry Thomas, Éditeur scientifique Editeur : Chichester : John Wiley & Sons Année de publication : 2000 Importance : xxvii, 539 p. Format : 24 cm ISBN/ISSN/EAN : 978-0-471-98807-6 Langues : Anglais (eng) Tags : PHARMACEUTICAL CHEMISTRY Index. décimale : EQ -Equipe- Résumé : "Medicinal Chemistry: An Introduction, provides a comprehensive, balanced introduction tot his exciting, evolving and multi-disciplinary field. Written in an accessible and readable style, this text carefully explains fundamental principles, assuming little in the way of prior knowledge. Focusing on the chemical principles used for drug discovery and design, it also covers human biology where relevant. The approach to medicinal chemistry is kept as simple as possible. Each chapter has a summary of its contents, self-assessment questions, numerous examples and applicaitons. Medicinal Chemistry: An Introduction: * Provides a comprehensive introduction to the field written in an accessible and readable style. * Assumes little prior knowledge of biology and a knowledge of chemistry to first year degree level. * Includes examples, applications, problems and summary sections in each chapter. Medicinal Chemistry: An Introduction will be invaluable to students of chemistry, medicinal and pharmaceutical chemsitry, pharmacy and pharmacology whose courses included medicinal chemistry units." Cote : LCC/K Num_Inv : 2587 Medicinal chemistry: An introduction [texte imprimé] / Garry Thomas, Éditeur scientifique . - Chichester : John Wiley & Sons, 2000 . - xxvii, 539 p. ; 24 cm. ISBN : 978-0-471-98807-6 Langues : Anglais (eng) Tags : PHARMACEUTICAL CHEMISTRY Index. décimale : EQ -Equipe- Résumé : "Medicinal Chemistry: An Introduction, provides a comprehensive, balanced introduction tot his exciting, evolving and multi-disciplinary field. Written in an accessible and readable style, this text carefully explains fundamental principles, assuming little in the way of prior knowledge. Focusing on the chemical principles used for drug discovery and design, it also covers human biology where relevant. The approach to medicinal chemistry is kept as simple as possible. Each chapter has a summary of its contents, self-assessment questions, numerous examples and applicaitons. Medicinal Chemistry: An Introduction: * Provides a comprehensive introduction to the field written in an accessible and readable style. * Assumes little prior knowledge of biology and a knowledge of chemistry to first year degree level. * Includes examples, applications, problems and summary sections in each chapter. Medicinal Chemistry: An Introduction will be invaluable to students of chemistry, medicinal and pharmaceutical chemsitry, pharmacy and pharmacology whose courses included medicinal chemistry units." Cote : LCC/K Num_Inv : 2587

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
2587	LCC/K	Texte imprimé	Equipe	Livre	Equipe - Demande préalable Disponible

Ligand design in medicinal inorganic chemistry / Tim Storr

Public ISBD Titre : Ligand design in medicinal inorganic chemistry Type de document : texte imprimé Auteurs : Tim Storr, Éditeur scientifique Editeur : Chichester : John Wiley & Sons Année de publication : 2014 Importance : xvii, 449 p. ISBN/ISSN/EAN : 978-1-118-48852-2 Langues : Anglais (eng) Catégories : Biochimie Tags : METALS-Therapeutic use  METALS IN MEDICINE  PHARMACEUTICAL CHEMISTRY  DNA-Drug interactions Index. décimale : B-F Note de contenu : "* Introduction to ligand design in medicinal inorganic chemistry * Platinum-based anticancer agents * Coordination chemistry and ligand design in the development of metal based radiopharmaceuticals * Ligand design in d-block optical imaging agents and sensors * Luminescent lanthanoid probes * Metal complexes of carbohydrate-targeted ligands in medicinal inorganic chemistry * Design of schiff base-derived ligands: Applications in therapeutics and medical diagnosis * Metal-based antimalarial agents * Therapeutic gold compounds * Ligand design to target and modulate metal–protein interactions in neurodegenerative diseases * Rational design of copper and iron chelators to treat Wilson’s disease and hemochromatosis * MRI contrast agents * Photoactivatable metal complexes and their use in biology and medicine * Metalloprotein inhibitors * Ruthenium anticancer compounds with biologically-derived ligands." Cote : B-F040 (SdS) Num_Inv : 3416 Ligand design in medicinal inorganic chemistry [texte imprimé] / Tim Storr, Éditeur scientifique . - Chichester : John Wiley & Sons, 2014 . - xvii, 449 p. ISBN : 978-1-118-48852-2 Langues : Anglais (eng) Catégories : Biochimie Tags : METALS-Therapeutic use  METALS IN MEDICINE  PHARMACEUTICAL CHEMISTRY  DNA-Drug interactions Index. décimale : B-F Note de contenu : "* Introduction to ligand design in medicinal inorganic chemistry * Platinum-based anticancer agents * Coordination chemistry and ligand design in the development of metal based radiopharmaceuticals * Ligand design in d-block optical imaging agents and sensors * Luminescent lanthanoid probes * Metal complexes of carbohydrate-targeted ligands in medicinal inorganic chemistry * Design of schiff base-derived ligands: Applications in therapeutics and medical diagnosis * Metal-based antimalarial agents * Therapeutic gold compounds * Ligand design to target and modulate metal–protein interactions in neurodegenerative diseases * Rational design of copper and iron chelators to treat Wilson’s disease and hemochromatosis * MRI contrast agents * Photoactivatable metal complexes and their use in biology and medicine * Metalloprotein inhibitors * Ruthenium anticancer compounds with biologically-derived ligands." Cote : B-F040 (SdS) Num_Inv : 3416

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
3416	B-F040	Texte imprimé	Bibliothèque	Livre	Disponible

Phosphorus ligands in asymmetric catalysis / Armin Börner

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Phosphorus ligands in asymmetric catalysis / Armin Börner

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Phosphorus ligands in asymmetric catalysis / Armin Börner

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Dénomination chimique : nomenclature et dénominations, applications aux substances pharmaceutiques / Association française des enseignants de chimie thérapeutique (AFECT)

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Drug-like properties / Edward Harvel Kerns

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