3 recherche sur le tag 'DRUG DEVELOPMENT'   

Applications of transition metal catalysis in drug discovery and development: An industrial perspective / Matthew L. Crawley

Public ISBD Titre : Applications of transition metal catalysis in drug discovery and development: An industrial perspective Type de document : texte imprimé Auteurs : Matthew L. Crawley, Éditeur scientifique ; Barry M. Trost, Éditeur scientifique Editeur : Hoboken : John Wiley & Sons Année de publication : 2012 Importance : xviii, 356 p. ISBN/ISSN/EAN : 978-0-470-63132-4 Langues : Anglais (eng) Catégories : Catalyse Tags : DRUG DEVELOPMENT  CATALYSIS  TRANSITION METALS Index. décimale : B-E Résumé : "This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs. The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discovery and development – it is a guide, a historical prospective, a practical compendium, and a source of future direction for the field." Cote : B-E079 (SdS) Num_Inv : 3445 Applications of transition metal catalysis in drug discovery and development: An industrial perspective [texte imprimé] / Matthew L. Crawley, Éditeur scientifique ; Barry M. Trost, Éditeur scientifique . - Hoboken : John Wiley & Sons, 2012 . - xviii, 356 p. ISBN : 978-0-470-63132-4 Langues : Anglais (eng) Catégories : Catalyse Tags : DRUG DEVELOPMENT  CATALYSIS  TRANSITION METALS Index. décimale : B-E Résumé : "This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs. The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discovery and development – it is a guide, a historical prospective, a practical compendium, and a source of future direction for the field." Cote : B-E079 (SdS) Num_Inv : 3445

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
3445	B-E079	Texte imprimé	Bibliothèque	Livre	Disponible

Neglected tropical diseases / Swinney, David C.

Public ISBD Titre : Neglected tropical diseases Type de document : texte imprimé Auteurs : Swinney, David C., Éditeur scientifique ; Pollastri, Michael P., Auteur Editeur : New York : John Wiley & Sons Année de publication : 2019 Collection : Drug discovery and development num. 77 Importance : xviii, 373 p. ISBN/ISSN/EAN : 978-3-527-34304-1 Langues : Anglais (eng) Catégories : Biochimie Tags : DRUG DEVELOPMENT Index. décimale : B-F Résumé : Neglected Tropical Diseases is the first book of its kind to offer a guide that follows the World Health Organization's list of neglected tropical diseases. The authors all are experts on the topiccaddress the development of effective treatments for 12 crippling infectious diseases that affect almost 20% of the world's popluation. The book includes information on the common approaches and the most important factors that lead to the development of new drugs for treating tropical diseases. Individual chapters review 12 neglected tropical diseases that are grouped by infectious agent, from viruses to bacteria to eukaryotic parasites. For each of these diseases, the book explains the unmet medical need and explores the current and potential drug discovery strategies. The book also includes information on potential drug compounds derived from natural products. Note de contenu : "* Drug Discovery Strategies for Neglected Tropical Diseases: Repurposing Knowledge, Mechanisms and Therapeutics to Increase Discovery Efficiency * Toward Antiviral Therapies for the Treatment of Zika Virus Infection: Lessons Learned from Dengue Virus * Developing Therapeutics for Ebola Virus Disease: A Multifaceted Approach * Designing Drugs to Target Trypanosoma cruzi, the Etiological Agent of Chagas Disease: When Chemistry needs Biology * Drug Discovery and Development for Human African Trypanosomiasis * Discovery of Drugs for Leishmaniases: A Progress Report * Onchocerciasis Drug Discovery * Drug Discovery and Development for Schistosomiasis * Soil-transmitted Helminthiasis – Challenges with Discovery of Novel Anthelmintics * Drug Discovery and Development for the Treatment of Echinococcosis, Caused by the Tapeworms Echinococcus granulosus and Echinococcus multilocularis * New Insights into the Treatment of Foodborne Trematode Infections * Buruli Ulcer * Drug Discovery and Development for Leprosy". Cote : B-F062 Num_Inv : 718 Localisation : LCC (SdS) Neglected tropical diseases [texte imprimé] / Swinney, David C., Éditeur scientifique ; Pollastri, Michael P., Auteur . - New York : John Wiley & Sons, 2019 . - xviii, 373 p.. - (Drug discovery and development; 77) . ISBN : 978-3-527-34304-1 Langues : Anglais (eng) Catégories : Biochimie Tags : DRUG DEVELOPMENT Index. décimale : B-F Résumé : Neglected Tropical Diseases is the first book of its kind to offer a guide that follows the World Health Organization's list of neglected tropical diseases. The authors all are experts on the topiccaddress the development of effective treatments for 12 crippling infectious diseases that affect almost 20% of the world's popluation. The book includes information on the common approaches and the most important factors that lead to the development of new drugs for treating tropical diseases. Individual chapters review 12 neglected tropical diseases that are grouped by infectious agent, from viruses to bacteria to eukaryotic parasites. For each of these diseases, the book explains the unmet medical need and explores the current and potential drug discovery strategies. The book also includes information on potential drug compounds derived from natural products. Note de contenu : "* Drug Discovery Strategies for Neglected Tropical Diseases: Repurposing Knowledge, Mechanisms and Therapeutics to Increase Discovery Efficiency * Toward Antiviral Therapies for the Treatment of Zika Virus Infection: Lessons Learned from Dengue Virus * Developing Therapeutics for Ebola Virus Disease: A Multifaceted Approach * Designing Drugs to Target Trypanosoma cruzi, the Etiological Agent of Chagas Disease: When Chemistry needs Biology * Drug Discovery and Development for Human African Trypanosomiasis * Discovery of Drugs for Leishmaniases: A Progress Report * Onchocerciasis Drug Discovery * Drug Discovery and Development for Schistosomiasis * Soil-transmitted Helminthiasis – Challenges with Discovery of Novel Anthelmintics * Drug Discovery and Development for the Treatment of Echinococcosis, Caused by the Tapeworms Echinococcus granulosus and Echinococcus multilocularis * New Insights into the Treatment of Foodborne Trematode Infections * Buruli Ulcer * Drug Discovery and Development for Leprosy". Cote : B-F062 Num_Inv : 718 Localisation : LCC (SdS)

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
718	B-F062	Texte imprimé	Bibliothèque	Livre	Disponible

Protein phosphorylation in parasites: Novel targets for antiparasitic intervention / Christian Doerig

Public ISBD Titre : Protein phosphorylation in parasites: Novel targets for antiparasitic intervention Type de document : texte imprimé Auteurs : Christian Doerig, Éditeur scientifique ; Gerald Spaeth, Éditeur scientifique ; Martin Wiese, Éditeur scientifique ; Paul M. Selzer, Éditeur scientifique Editeur : Weinheim : Wiley-VCH Année de publication : 2013 Collection : Drug Discovery in Infectious Diseases Series num. 5 Importance : xxii, 428 p. ISBN/ISSN/EAN : 978-3-527-33235-9 Langues : Anglais (eng) Catégories : Biochimie Tags : PARASITIC DISEASES-Treatment  DRUG DEVELOPMENT  PHOSPHOPROTEIN PHOSPHATASES-Therapeutic use  PROTEIN KINASES-Therapeutic use Index. décimale : B-F Résumé : "This is the first book to collect and summarize in one publication the efforts to use kinases or phosphatases for drug development against parasite infections. The editors and contributors comprise the Who is Who in the field, and they are comprehensive in covering every aspect of the topic, from basic research findings to translational approaches in drug development. The result will be welcomed by everyone in academia and industry participating in the global effort to finally combat the major diseases caused by eukaryotic parasites. This is volume one of a two-volume treatise, the second being exclusively dedicated to efforts to combat malaria using the same approach." Note de contenu : "* Part I: Bioinformatics * Part II: Funtional analysis of parasite kinomes and phosphatomes * Part III: Role of host cell kinomes and phospatomes in parasitic infections * Part IV: Drug discovery." Cote : B-F039 (SdS) Num_Inv : 3413 Protein phosphorylation in parasites: Novel targets for antiparasitic intervention [texte imprimé] / Christian Doerig, Éditeur scientifique ; Gerald Spaeth, Éditeur scientifique ; Martin Wiese, Éditeur scientifique ; Paul M. Selzer, Éditeur scientifique . - Weinheim : Wiley-VCH, 2013 . - xxii, 428 p.. - (Drug Discovery in Infectious Diseases Series; 5) . ISBN : 978-3-527-33235-9 Langues : Anglais (eng) Catégories : Biochimie Tags : PARASITIC DISEASES-Treatment  DRUG DEVELOPMENT  PHOSPHOPROTEIN PHOSPHATASES-Therapeutic use  PROTEIN KINASES-Therapeutic use Index. décimale : B-F Résumé : "This is the first book to collect and summarize in one publication the efforts to use kinases or phosphatases for drug development against parasite infections. The editors and contributors comprise the Who is Who in the field, and they are comprehensive in covering every aspect of the topic, from basic research findings to translational approaches in drug development. The result will be welcomed by everyone in academia and industry participating in the global effort to finally combat the major diseases caused by eukaryotic parasites. This is volume one of a two-volume treatise, the second being exclusively dedicated to efforts to combat malaria using the same approach." Note de contenu : "* Part I: Bioinformatics * Part II: Funtional analysis of parasite kinomes and phosphatomes * Part III: Role of host cell kinomes and phospatomes in parasitic infections * Part IV: Drug discovery." Cote : B-F039 (SdS) Num_Inv : 3413

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
3413	B-F039	Texte imprimé	Bibliothèque	Livre	Disponible