2 recherche sur le tag 'FLUORINE'   

Fluorine in medicinal chemistry and chemical biology / Iwao Ojima

Public ISBD Titre : Fluorine in medicinal chemistry and chemical biology Type de document : texte imprimé Auteurs : Iwao Ojima, Éditeur scientifique Editeur : Oxford : Wiley-Blackwell Année de publication : 2009 Importance : xvi, 624 p. Format : 26 cm ISBN/ISSN/EAN : 978-1-4051-6720-8 Langues : Anglais (eng) Catégories : Biochimie Tags : ORGANOFLUORINE COMPOUNDS  FLUORINE  BIOORGANIC CHEMISTRY  PHARMACEUTICAL CHEMISTRY Index. décimale : B-F Résumé : "The extraordinary potential of fluorine-containing molecules in medicinal chemistry and chemical biology has been recognized by researchers outside of the traditional fluorine chemistry field, and thus a new wave of fluorine chemistry is rapidly expanding its biomedical frontiers. With several of the best selling drugs in the world crucially containing fluorine atoms, the incorporation of fluorine to drug leads has become an essential practice in biomedical research, especially for drug design and discovery as well as development. Focusing on the unique and significant roles that fluorine plays in medicinal chemistry and chemical biology, this book reviews recent advances and future prospects in this rapidly developing field. Topics covered include: * Discovery and development of fluorine containing drugs and drug candidates. * New and efficient synthetic methods for medicinal chemistry and the optimisation of fluorine-containing drug candidates. * Structural and chemical biology of fluorinated amino acids and peptides. * Fluorine labels as probes in metabolic study, protein engineering and clinical diagnosis. * Applications of 19F NMR spectroscopy in biomedical research. An appendix presents an invaluable index of all fluorine-containing drugs that have been approved by the US Food and Drug Administration, including information on structure and pharmaceutical action. Fluorine in Medicinal Chemistry and Chemical Biology will serve as an excellent reference source for graduate students as well as academic and industrial researchers who want to take advantage of fluorine in biomedical research." Cote : B-F032 (SdS) Num_Inv : 2894 Fluorine in medicinal chemistry and chemical biology [texte imprimé] / Iwao Ojima, Éditeur scientifique . - Oxford : Wiley-Blackwell, 2009 . - xvi, 624 p. ; 26 cm. ISBN : 978-1-4051-6720-8 Langues : Anglais (eng) Catégories : Biochimie Tags : ORGANOFLUORINE COMPOUNDS  FLUORINE  BIOORGANIC CHEMISTRY  PHARMACEUTICAL CHEMISTRY Index. décimale : B-F Résumé : "The extraordinary potential of fluorine-containing molecules in medicinal chemistry and chemical biology has been recognized by researchers outside of the traditional fluorine chemistry field, and thus a new wave of fluorine chemistry is rapidly expanding its biomedical frontiers. With several of the best selling drugs in the world crucially containing fluorine atoms, the incorporation of fluorine to drug leads has become an essential practice in biomedical research, especially for drug design and discovery as well as development. Focusing on the unique and significant roles that fluorine plays in medicinal chemistry and chemical biology, this book reviews recent advances and future prospects in this rapidly developing field. Topics covered include: * Discovery and development of fluorine containing drugs and drug candidates. * New and efficient synthetic methods for medicinal chemistry and the optimisation of fluorine-containing drug candidates. * Structural and chemical biology of fluorinated amino acids and peptides. * Fluorine labels as probes in metabolic study, protein engineering and clinical diagnosis. * Applications of 19F NMR spectroscopy in biomedical research. An appendix presents an invaluable index of all fluorine-containing drugs that have been approved by the US Food and Drug Administration, including information on structure and pharmaceutical action. Fluorine in Medicinal Chemistry and Chemical Biology will serve as an excellent reference source for graduate students as well as academic and industrial researchers who want to take advantage of fluorine in biomedical research." Cote : B-F032 (SdS) Num_Inv : 2894

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
2894	B-F032	Texte imprimé	Bibliothèque	Livre	Disponible

Handbook of fluorous chemistry / John A. Gladysz

Public ISBD Titre : Handbook of fluorous chemistry Type de document : texte imprimé Auteurs : John A. Gladysz, Éditeur scientifique ; Dennis P. Curran, Éditeur scientifique ; Istvan T. Horvath, Éditeur scientifique Editeur : Weinheim : Wiley-VCH Année de publication : 2004 Importance : xix, 595 p. Format : 25 cm ISBN/ISSN/EAN : 978-3-527-30617-6 Langues : Anglais (eng) Catégories : Catalyse Tags : FLUORINE COMPOUNDS  FLUORINE Index. décimale : B-E Résumé : "Edited by the leading experts John Gladysz, Dennis Curran, and Istvan Horvath, this handbook is the first to summarize all the essential aspects of this emerging field of chemistry. Whether the reader is seeking an introduction to the concept of fluorous biphase catalysis, summaries of partition coefficients involving fluorous and organic solvents, or information on the latest fluorous mixture separation techniques, this authoritative compilation of contributions, written by the world's top authors, provides key information needed for successfully working with the diverse and fascinating families of fluorous molecules. The large number of reliable experimental procedures in particular makes this the ideal guide for newcomers wanting to use this elegant method in the laboratory. In addition, experts will also find a wealth of important information concisely contained in one ready reference. The result is an indispensable resource for everyone currently working or intending to work in this field." Cote : B-E036 (SdS) Num_Inv : 2910 Handbook of fluorous chemistry [texte imprimé] / John A. Gladysz, Éditeur scientifique ; Dennis P. Curran, Éditeur scientifique ; Istvan T. Horvath, Éditeur scientifique . - Weinheim : Wiley-VCH, 2004 . - xix, 595 p. ; 25 cm. ISBN : 978-3-527-30617-6 Langues : Anglais (eng) Catégories : Catalyse Tags : FLUORINE COMPOUNDS  FLUORINE Index. décimale : B-E Résumé : "Edited by the leading experts John Gladysz, Dennis Curran, and Istvan Horvath, this handbook is the first to summarize all the essential aspects of this emerging field of chemistry. Whether the reader is seeking an introduction to the concept of fluorous biphase catalysis, summaries of partition coefficients involving fluorous and organic solvents, or information on the latest fluorous mixture separation techniques, this authoritative compilation of contributions, written by the world's top authors, provides key information needed for successfully working with the diverse and fascinating families of fluorous molecules. The large number of reliable experimental procedures in particular makes this the ideal guide for newcomers wanting to use this elegant method in the laboratory. In addition, experts will also find a wealth of important information concisely contained in one ready reference. The result is an indispensable resource for everyone currently working or intending to work in this field." Cote : B-E036 (SdS) Num_Inv : 2910

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
2910	B-E036	Texte imprimé	Bibliothèque	Livre	Disponible