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Titre : |
Medicinal chemistry : The role of organic chemistry in drug research |
Type de document : |
texte imprimé |
Auteurs : |
Ganellin, C. R., Éditeur scientifique ; Roberts, S. M., Auteur |
Editeur : |
London : Academic Press |
Année de publication : |
1992 |
Importance : |
250 p. |
ISBN/ISSN/EAN : |
978-0-12-274120-3 |
Langues : |
Anglais (eng) |
Catégories : |
Biochimie
|
Tags : |
BIOCHEMISTRY MEDICINAL CHEMISTRY ORGANIC CHEMISTRY |
Index. décimale : |
B-F |
Résumé : |
This Second Edition covers exciting progress recently made with individual drugs and includes a special chapter on the impact of molecular biology on drug design. Other additions to the Second Edition include structure-activity relationships, the role of molecular biology in drug discovery, and drug access and prodrugs. Written for students considering a research career in drug development, this volume is conveniently divided into two parts. The first half introduces readers to the mechanisms of action of drugs and the approaches adopted in designing new drugs. The second half contains chapters written by the discoverers or developers of individual successful drugs who trace the history of the drugs to the present day. |
Cote : |
B-F056 |
Num_Inv : |
3597 |
Localisation : |
LCC (SdS) |
Medicinal chemistry : The role of organic chemistry in drug research [texte imprimé] / Ganellin, C. R., Éditeur scientifique ; Roberts, S. M., Auteur . - London : Academic Press, 1992 . - 250 p. ISBN : 978-0-12-274120-3 Langues : Anglais ( eng)
Catégories : |
Biochimie
|
Tags : |
BIOCHEMISTRY MEDICINAL CHEMISTRY ORGANIC CHEMISTRY |
Index. décimale : |
B-F |
Résumé : |
This Second Edition covers exciting progress recently made with individual drugs and includes a special chapter on the impact of molecular biology on drug design. Other additions to the Second Edition include structure-activity relationships, the role of molecular biology in drug discovery, and drug access and prodrugs. Written for students considering a research career in drug development, this volume is conveniently divided into two parts. The first half introduces readers to the mechanisms of action of drugs and the approaches adopted in designing new drugs. The second half contains chapters written by the discoverers or developers of individual successful drugs who trace the history of the drugs to the present day. |
Cote : |
B-F056 |
Num_Inv : |
3597 |
Localisation : |
LCC (SdS) |
|  |
Exemplaires(1)
3597
|
B-F056 |
Texte imprimé |
Bibliothèque |
Livre
|
Disponible |

Titre : |
Bioinorganic medicinal chemistry |
Type de document : |
texte imprimé |
Auteurs : |
Alessio, Enzo, Auteur |
Editeur : |
Wiley-VCH Verlag |
Année de publication : |
2011 |
Importance : |
xiii, 422 p. |
ISBN/ISSN/EAN : |
978-3-527-32631-0 |
Note générale : |
This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic. |
Langues : |
Anglais (eng) |
Catégories : |
Biochimie
|
Tags : |
BIOCHEMISTRY MEDICINAL CHEMISTRY BIOINORGANIC CHEMISTRY |
Index. décimale : |
B-F |
Résumé : |
This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic. |
Note de contenu : |
"* Medicinal inorganic chemistry: state of the art, new trends, and a vision of the future
* Targeting strategies for metal-based therapeutics
* Current status and mechanism of action of platinum-based anticancer drugs
* New trends and future developments of platinum-based antitumor drugs
* Ruthenium and other non-platinum anticancer compounds
* The challenge of establishing reliable screening tests for selecting anticancer metal compounds
* Gold-based therapeutic agents: a new perspective
* MRI contrast agents: state of the art and new trends
* Metal-based radiopharmaceuticals
* Boron and gadolinium in the neutron capture therapy of cancer
* Essential metal related metabolic disorders
* Metal compounds as enzyme inhibitors
* Biomedical applications of metal-containing luminophores" |
Cote : |
B-F052 |
Num_Inv : |
3532 |
Localisation : |
LCC (SdS) |
Bioinorganic medicinal chemistry [texte imprimé] / Alessio, Enzo, Auteur . - Wiley-VCH Verlag, 2011 . - xiii, 422 p. ISBN : 978-3-527-32631-0 This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic. Langues : Anglais ( eng)
Catégories : |
Biochimie
|
Tags : |
BIOCHEMISTRY MEDICINAL CHEMISTRY BIOINORGANIC CHEMISTRY |
Index. décimale : |
B-F |
Résumé : |
This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic. |
Note de contenu : |
"* Medicinal inorganic chemistry: state of the art, new trends, and a vision of the future
* Targeting strategies for metal-based therapeutics
* Current status and mechanism of action of platinum-based anticancer drugs
* New trends and future developments of platinum-based antitumor drugs
* Ruthenium and other non-platinum anticancer compounds
* The challenge of establishing reliable screening tests for selecting anticancer metal compounds
* Gold-based therapeutic agents: a new perspective
* MRI contrast agents: state of the art and new trends
* Metal-based radiopharmaceuticals
* Boron and gadolinium in the neutron capture therapy of cancer
* Essential metal related metabolic disorders
* Metal compounds as enzyme inhibitors
* Biomedical applications of metal-containing luminophores" |
Cote : |
B-F052 |
Num_Inv : |
3532 |
Localisation : |
LCC (SdS) |
|  |
Réservation
Réserver ce document
Exemplaires(1)
3532
|
B-F052 |
Texte imprimé |
Bibliothèque |
Livre
|
Sorti jusqu'au 14/03/2022 |

Titre : |
Computer-assisted lead finding and optimization: Current tools for medicinal chemistry |
Type de document : |
texte imprimé |
Auteurs : |
Han Van de Waterbeemd, Éditeur scientifique ; Bernard Testa, Éditeur scientifique ; Gerd Folkers, Éditeur scientifique |
Editeur : |
Zurich : Helvetica Chimica Acta |
Année de publication : |
1997 |
Autre Editeur : |
Weinheim : Wiley-VCH |
Importance : |
553 p. |
ISBN/ISSN/EAN : |
978-3-906390-16-1 |
Langues : |
Anglais (eng) |
Tags : |
COMPUTER-ASSISTED LEAD FINDING MEDICINAL CHEMISTRY |
Index. décimale : |
EQ -Equipe- |
Résumé : |
"Computer-assisted techniques are well-integrated in modern drug discovery and used for the finding of new leads, the optimization of receptor or enzyme affinity, as well as of pharmacokinetic and physicochemical properties.
In this book an account is found of current strategies used in computer-assisted drug design. Important topics include progress in chemometrics, molecular modeling and three-dimensional QSAR approaches. Relatively new mathematical methods such as genetic algorithms or artificial neural networks and fuzzy logic have found their application in rational molecular design. As is amply illustrated, based on recent developments in these disciplines, important progress has been made in lead finding strategies. This is of great importance to the pharmaceutical industry.
Thus, all scientists investigating quantitative structure-activity relationships in their broadest sense, in medicinal, agricultural, or environmental chemistry will benefit from this book." |
Cote : |
LCC/K |
Num_Inv : |
2418 |
Computer-assisted lead finding and optimization: Current tools for medicinal chemistry [texte imprimé] / Han Van de Waterbeemd, Éditeur scientifique ; Bernard Testa, Éditeur scientifique ; Gerd Folkers, Éditeur scientifique . - Zurich : Helvetica Chimica Acta : Weinheim : Wiley-VCH, 1997 . - 553 p. ISBN : 978-3-906390-16-1 Langues : Anglais ( eng)
Tags : |
COMPUTER-ASSISTED LEAD FINDING MEDICINAL CHEMISTRY |
Index. décimale : |
EQ -Equipe- |
Résumé : |
"Computer-assisted techniques are well-integrated in modern drug discovery and used for the finding of new leads, the optimization of receptor or enzyme affinity, as well as of pharmacokinetic and physicochemical properties.
In this book an account is found of current strategies used in computer-assisted drug design. Important topics include progress in chemometrics, molecular modeling and three-dimensional QSAR approaches. Relatively new mathematical methods such as genetic algorithms or artificial neural networks and fuzzy logic have found their application in rational molecular design. As is amply illustrated, based on recent developments in these disciplines, important progress has been made in lead finding strategies. This is of great importance to the pharmaceutical industry.
Thus, all scientists investigating quantitative structure-activity relationships in their broadest sense, in medicinal, agricultural, or environmental chemistry will benefit from this book." |
Cote : |
LCC/K |
Num_Inv : |
2418 |
|  |
Exemplaires(1)
2418
|
LCC/K |
Texte imprimé |
Equipe |
Livre
|
Equipe - Demande préalable Disponible |
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