3 recherche sur le tag 'MEDICINAL CHEMISTRY'   

Medicinal chemistry / Ganellin, C. R.

Public ISBD Titre : Medicinal chemistry : The role of organic chemistry in drug research Type de document : texte imprimé Auteurs : Ganellin, C. R., Éditeur scientifique ; Roberts, S. M., Auteur Editeur : London : Academic Press Année de publication : 1992 Importance : 250 p. ISBN/ISSN/EAN : 978-0-12-274120-3 Langues : Anglais (eng) Catégories : Biochimie Tags : BIOCHEMISTRY  MEDICINAL CHEMISTRY  ORGANIC CHEMISTRY Index. décimale : B-F Résumé : This Second Edition covers exciting progress recently made with individual drugs and includes a special chapter on the impact of molecular biology on drug design. Other additions to the Second Edition include structure-activity relationships, the role of molecular biology in drug discovery, and drug access and prodrugs. Written for students considering a research career in drug development, this volume is conveniently divided into two parts. The first half introduces readers to the mechanisms of action of drugs and the approaches adopted in designing new drugs. The second half contains chapters written by the discoverers or developers of individual successful drugs who trace the history of the drugs to the present day. Cote : B-F056 Num_Inv : 3597 Localisation : LCC (SdS) Medicinal chemistry : The role of organic chemistry in drug research [texte imprimé] / Ganellin, C. R., Éditeur scientifique ; Roberts, S. M., Auteur . - London : Academic Press, 1992 . - 250 p. ISBN : 978-0-12-274120-3 Langues : Anglais (eng) Catégories : Biochimie Tags : BIOCHEMISTRY  MEDICINAL CHEMISTRY  ORGANIC CHEMISTRY Index. décimale : B-F Résumé : This Second Edition covers exciting progress recently made with individual drugs and includes a special chapter on the impact of molecular biology on drug design. Other additions to the Second Edition include structure-activity relationships, the role of molecular biology in drug discovery, and drug access and prodrugs. Written for students considering a research career in drug development, this volume is conveniently divided into two parts. The first half introduces readers to the mechanisms of action of drugs and the approaches adopted in designing new drugs. The second half contains chapters written by the discoverers or developers of individual successful drugs who trace the history of the drugs to the present day. Cote : B-F056 Num_Inv : 3597 Localisation : LCC (SdS)

Exemplaires(1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
3597	B-F056	Texte imprimé	Bibliothèque	Livre	Disponible

Bioinorganic medicinal chemistry / Alessio, Enzo

Public ISBD Titre : Bioinorganic medicinal chemistry Type de document : texte imprimé Auteurs : Alessio, Enzo, Auteur Editeur : Wiley-VCH Verlag Année de publication : 2011 Importance : xiii, 422 p. ISBN/ISSN/EAN : 978-3-527-32631-0 Note générale : This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic. Langues : Anglais (eng) Catégories : Biochimie Tags : BIOCHEMISTRY  MEDICINAL CHEMISTRY  BIOINORGANIC CHEMISTRY Index. décimale : B-F Résumé : This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic. Note de contenu : "* Medicinal inorganic chemistry: state of the art, new trends, and a vision of the future * Targeting strategies for metal-based therapeutics * Current status and mechanism of action of platinum-based anticancer drugs * New trends and future developments of platinum-based antitumor drugs * Ruthenium and other non-platinum anticancer compounds * The challenge of establishing reliable screening tests for selecting anticancer metal compounds * Gold-based therapeutic agents: a new perspective * MRI contrast agents: state of the art and new trends * Metal-based radiopharmaceuticals * Boron and gadolinium in the neutron capture therapy of cancer * Essential metal related metabolic disorders * Metal compounds as enzyme inhibitors * Biomedical applications of metal-containing luminophores" Cote : B-F052 Num_Inv : 3532 Localisation : LCC (SdS) Bioinorganic medicinal chemistry [texte imprimé] / Alessio, Enzo, Auteur . - Wiley-VCH Verlag, 2011 . - xiii, 422 p. ISBN : 978-3-527-32631-0 This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic. Langues : Anglais (eng) Catégories : Biochimie Tags : BIOCHEMISTRY  MEDICINAL CHEMISTRY  BIOINORGANIC CHEMISTRY Index. décimale : B-F Résumé : This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic. Note de contenu : "* Medicinal inorganic chemistry: state of the art, new trends, and a vision of the future * Targeting strategies for metal-based therapeutics * Current status and mechanism of action of platinum-based anticancer drugs * New trends and future developments of platinum-based antitumor drugs * Ruthenium and other non-platinum anticancer compounds * The challenge of establishing reliable screening tests for selecting anticancer metal compounds * Gold-based therapeutic agents: a new perspective * MRI contrast agents: state of the art and new trends * Metal-based radiopharmaceuticals * Boron and gadolinium in the neutron capture therapy of cancer * Essential metal related metabolic disorders * Metal compounds as enzyme inhibitors * Biomedical applications of metal-containing luminophores" Cote : B-F052 Num_Inv : 3532 Localisation : LCC (SdS)

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Code-barres	Cote	Support	Localisation	Section	Disponibilité
3532	B-F052	Texte imprimé	Bibliothèque	Livre	Sorti jusqu'au 14/03/2022

Computer-assisted lead finding and optimization: Current tools for medicinal chemistry / Han Van de Waterbeemd

Public ISBD Titre : Computer-assisted lead finding and optimization: Current tools for medicinal chemistry Type de document : texte imprimé Auteurs : Han Van de Waterbeemd, Éditeur scientifique ; Bernard Testa, Éditeur scientifique ; Gerd Folkers, Éditeur scientifique Editeur : Zurich : Helvetica Chimica Acta Année de publication : 1997 Autre Editeur : Weinheim : Wiley-VCH Importance : 553 p. ISBN/ISSN/EAN : 978-3-906390-16-1 Langues : Anglais (eng) Tags : COMPUTER-ASSISTED LEAD FINDING  MEDICINAL CHEMISTRY Index. décimale : EQ -Equipe- Résumé : "Computer-assisted techniques are well-integrated in modern drug discovery and used for the finding of new leads, the optimization of receptor or enzyme affinity, as well as of pharmacokinetic and physicochemical properties. In this book an account is found of current strategies used in computer-assisted drug design. Important topics include progress in chemometrics, molecular modeling and three-dimensional QSAR approaches. Relatively new mathematical methods such as genetic algorithms or artificial neural networks and fuzzy logic have found their application in rational molecular design. As is amply illustrated, based on recent developments in these disciplines, important progress has been made in lead finding strategies. This is of great importance to the pharmaceutical industry. Thus, all scientists investigating quantitative structure-activity relationships in their broadest sense, in medicinal, agricultural, or environmental chemistry will benefit from this book." Cote : LCC/K Num_Inv : 2418 Computer-assisted lead finding and optimization: Current tools for medicinal chemistry [texte imprimé] / Han Van de Waterbeemd, Éditeur scientifique ; Bernard Testa, Éditeur scientifique ; Gerd Folkers, Éditeur scientifique . - Zurich : Helvetica Chimica Acta : Weinheim : Wiley-VCH, 1997 . - 553 p. ISBN : 978-3-906390-16-1 Langues : Anglais (eng) Tags : COMPUTER-ASSISTED LEAD FINDING  MEDICINAL CHEMISTRY Index. décimale : EQ -Equipe- Résumé : "Computer-assisted techniques are well-integrated in modern drug discovery and used for the finding of new leads, the optimization of receptor or enzyme affinity, as well as of pharmacokinetic and physicochemical properties. In this book an account is found of current strategies used in computer-assisted drug design. Important topics include progress in chemometrics, molecular modeling and three-dimensional QSAR approaches. Relatively new mathematical methods such as genetic algorithms or artificial neural networks and fuzzy logic have found their application in rational molecular design. As is amply illustrated, based on recent developments in these disciplines, important progress has been made in lead finding strategies. This is of great importance to the pharmaceutical industry. Thus, all scientists investigating quantitative structure-activity relationships in their broadest sense, in medicinal, agricultural, or environmental chemistry will benefit from this book." Cote : LCC/K Num_Inv : 2418

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Code-barres	Cote	Support	Localisation	Section	Disponibilité
2418	LCC/K	Texte imprimé	Equipe	Livre	Equipe - Demande préalable Disponible