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Combinatorial chemistry / Jung, Günther
Titre : Combinatorial chemistry : Synthesis, analysis, screening Type de document : texte imprimé Auteurs : Jung, Günther, Éditeur scientifique Editeur : Oxford : Wiley Année de publication : 1999 Importance : 634 p. ISBN/ISSN/EAN : 978-3-527-29869-3 Langues : Anglais (eng) Catégories : Chimie de coordination, Chimie organométallique, Métaux de transition Tags : BIOCHEMISTRY APPLICATIONS ORGANOMETALLIC-SYNTHESIS Index. décimale : B-D Résumé : Combinatorial chemistry is a proven time- and resource-saving synthetic method of outstanding importance for industrial processes. Compound libraries help to save time and money, especially in the search for new drugs, and therefore play a pivotal role in solving the problem of the worldwide increasing demand for new and more active drugs. Not only substances, which are of interest for pharmaceutical chemistry, but also materials, catalysts, and biomolecules such as DNA or oligosaccharides are readily available with high structural diversities. The broad scope of combinatorial sciences is reflected by this book, edited by Günther Jung: The synthetic methods discussed range from solid-phase to solution-phase synthesis, from preparations of small molecules such as amines or alcohols to those of complex biomolecules. Feasible methods, efficient techniques, new trends in automation, and state-of-the-art fast instrumental analytical and screening methods are presented with many practical tips and tricks for everybody working in combinatorial chemistry. Note de contenu : "* Combinatorial Chemistry
Survey of Solid?Phase Organic Reactions
Solution?Phase Combinatorial Chemistry
Combinatorial Chemistry of Multicomponent Reactions
Solid?Phase Anchors in Organic Chemistry
The Use of Templates in Combinatorial Chemistry for the Solid?Phase Synthesis of Multiple Core Structure Libraries
Combinatorial Synthetic Oligomers
Glycopeptide and Oligosaccharide Libraries
RNA and DNA Aptamers
Combinatorial Approaches to Molecular Receptors for Chemosensors
Peptide Libraries in T?Cell?Mediated Immune Response
Combinatorial Biosynthesis of Microbial Metabolites
Design and Diversity Analysis of Compound Libraries for Lead Discovery
How to Scale?up while Scaling down: EVOscreen™, a Miniaturized Ultra?High?Throughput Screening System
High?Throughput Experimentation in Catalysis
FT?Infrared Spectroscopy and IR?Microscopy On?Bead Analysis of Solid?Phase Synthesis
Mass Spectrometric Analysis of Combinatorially Generated Compounds and Libraries
High?Resolution Magic Angle Spinning (MAS) NMR Spectroscopy for On?Bead Analysis of Solid?Phase Synthesis
Automated Combinatorial Chemistry
Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (FT?ICR?MS) for Analysis of Compound Libraries".Cote : B-D207 Num_Inv : 3595 Localisation : LCC (SdS) Combinatorial chemistry : Synthesis, analysis, screening [texte imprimé] / Jung, Günther, Éditeur scientifique . - Oxford : Wiley, 1999 . - 634 p.
ISBN : 978-3-527-29869-3
Langues : Anglais (eng)
Catégories : Chimie de coordination, Chimie organométallique, Métaux de transition Tags : BIOCHEMISTRY APPLICATIONS ORGANOMETALLIC-SYNTHESIS Index. décimale : B-D Résumé : Combinatorial chemistry is a proven time- and resource-saving synthetic method of outstanding importance for industrial processes. Compound libraries help to save time and money, especially in the search for new drugs, and therefore play a pivotal role in solving the problem of the worldwide increasing demand for new and more active drugs. Not only substances, which are of interest for pharmaceutical chemistry, but also materials, catalysts, and biomolecules such as DNA or oligosaccharides are readily available with high structural diversities. The broad scope of combinatorial sciences is reflected by this book, edited by Günther Jung: The synthetic methods discussed range from solid-phase to solution-phase synthesis, from preparations of small molecules such as amines or alcohols to those of complex biomolecules. Feasible methods, efficient techniques, new trends in automation, and state-of-the-art fast instrumental analytical and screening methods are presented with many practical tips and tricks for everybody working in combinatorial chemistry. Note de contenu : "* Combinatorial Chemistry
Survey of Solid?Phase Organic Reactions
Solution?Phase Combinatorial Chemistry
Combinatorial Chemistry of Multicomponent Reactions
Solid?Phase Anchors in Organic Chemistry
The Use of Templates in Combinatorial Chemistry for the Solid?Phase Synthesis of Multiple Core Structure Libraries
Combinatorial Synthetic Oligomers
Glycopeptide and Oligosaccharide Libraries
RNA and DNA Aptamers
Combinatorial Approaches to Molecular Receptors for Chemosensors
Peptide Libraries in T?Cell?Mediated Immune Response
Combinatorial Biosynthesis of Microbial Metabolites
Design and Diversity Analysis of Compound Libraries for Lead Discovery
How to Scale?up while Scaling down: EVOscreen™, a Miniaturized Ultra?High?Throughput Screening System
High?Throughput Experimentation in Catalysis
FT?Infrared Spectroscopy and IR?Microscopy On?Bead Analysis of Solid?Phase Synthesis
Mass Spectrometric Analysis of Combinatorially Generated Compounds and Libraries
High?Resolution Magic Angle Spinning (MAS) NMR Spectroscopy for On?Bead Analysis of Solid?Phase Synthesis
Automated Combinatorial Chemistry
Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (FT?ICR?MS) for Analysis of Compound Libraries".Cote : B-D207 Num_Inv : 3595 Localisation : LCC (SdS) Exemplaires(1)
Code-barres Cote Support Localisation Section Disponibilité 3595 B-D207 Texte imprimé Bibliothèque Livre Disponible Advances in Dendritic Macromolecules. Volume 4 / George R. Newkome
Titre : Advances in Dendritic Macromolecules. Volume 4 Type de document : texte imprimé Auteurs : George R. Newkome, Éditeur scientifique ; M. A. Hearshaw, Éditeur scientifique ; M. H. P. Van Genderen, Éditeur scientifique ; Hak-Fun Chow, Éditeur scientifique Editeur : London [England] : Jai Press Année de publication : 1999 Importance : 206 p. ISBN/ISSN/EAN : 978-0-7623-0347-2 Langues : Anglais (eng) Tags : ORGANOMETALLIC-Synthesis DENDRIMERS Index. décimale : EQ -Equipe- Résumé : 3The field of hyperbranched macromolecules, specifically dendrimers, has continued to expand at an amazing rate. The synthetic aspects, which were assumed to be over several years ago, have opened new avenues into the mesomolecular regime. The synthetic ingenuity of chemical artists has afforded new monomers and their diverse combinations to give rise to (poly)functionalized materials that embrace new supramolecular concepts in areas such as molecular recognition, assembly, encapsulation, and inclusion; catalysts; coatings; drug delivery systems; and in essence opens up the field of suprasupermolecular chemistry. In chapter 1 the synthesis of organometallic and related transition metal-cotaining dendrimers is summarized and their novel properties and useful applications are described. Chapter 2 covers work on the commercial poly(propylene imine)s, including the "dendritic box", dendrimer-based superamphiphiles, and unimolecular inverse micelles. The next chapter looks at aspects of chirality in dendritic systems and this is followed by a look inside dendrimers from a molecular topologist's point-of-view." Cote : LCC/M Num_Inv : 1654 Advances in Dendritic Macromolecules. Volume 4 [texte imprimé] / George R. Newkome, Éditeur scientifique ; M. A. Hearshaw, Éditeur scientifique ; M. H. P. Van Genderen, Éditeur scientifique ; Hak-Fun Chow, Éditeur scientifique . - London [England] : Jai Press, 1999 . - 206 p.
ISBN : 978-0-7623-0347-2
Langues : Anglais (eng)
Tags : ORGANOMETALLIC-Synthesis DENDRIMERS Index. décimale : EQ -Equipe- Résumé : 3The field of hyperbranched macromolecules, specifically dendrimers, has continued to expand at an amazing rate. The synthetic aspects, which were assumed to be over several years ago, have opened new avenues into the mesomolecular regime. The synthetic ingenuity of chemical artists has afforded new monomers and their diverse combinations to give rise to (poly)functionalized materials that embrace new supramolecular concepts in areas such as molecular recognition, assembly, encapsulation, and inclusion; catalysts; coatings; drug delivery systems; and in essence opens up the field of suprasupermolecular chemistry. In chapter 1 the synthesis of organometallic and related transition metal-cotaining dendrimers is summarized and their novel properties and useful applications are described. Chapter 2 covers work on the commercial poly(propylene imine)s, including the "dendritic box", dendrimer-based superamphiphiles, and unimolecular inverse micelles. The next chapter looks at aspects of chirality in dendritic systems and this is followed by a look inside dendrimers from a molecular topologist's point-of-view." Cote : LCC/M Num_Inv : 1654 Exemplaires(1)
Code-barres Cote Support Localisation Section Disponibilité 1654 LCC/M Texte imprimé Equipe Livre Equipe - Demande préalable
DisponibleCarbon dioxide activation by metal complexes / Behr, Arno
Titre : Carbon dioxide activation by metal complexes Type de document : texte imprimé Auteurs : Behr, Arno, Auteur Editeur : Wiley-VCH Verlag Année de publication : 1988 Importance : viii, 161 p. ISBN/ISSN/EAN : 978-0-89573-826-4 Langues : Français (fre) Catégories : Chimie de coordination, Chimie organométallique, Métaux de transition Tags : APPLICATIONS ORGANOMETALLIC-SYNTHESIS CARBON DIOXIDE Index. décimale : B-D Résumé : This book reviews the activation of carbon dioxide by metal complexes, covering all aspects of organometalic chemistry, homegeneous catalysis, and indstrial applications. It demonstrate the close relationship between stoichiometric and catalytic reactions of CO2 with organic substrates invlovingtransition metal complexes. The author illustrates the fascination of this research area which has become the focus of attention for numerous chemical disciplines: bio-, electro-, photo- and polymer chemistry. He reveals that in CO2 chemistry many novelties are still to be discovered, and that completely new synthetic routes to industrially interesting compounds seem possible. 800 references up to 1987 provide a convenient and comprehensive overview of the subject. Note de contenu : "* Carbon dixide as raw material
* Aims of the present review
* Stoichiometric reactions of carbon dioxide on transition metal centers
* Catalytic reactions of carbon dioxide at transition metal complexes"Cote : B-D208 Num_Inv : 3596 Localisation : LCC (SdS) Carbon dioxide activation by metal complexes [texte imprimé] / Behr, Arno, Auteur . - Wiley-VCH Verlag, 1988 . - viii, 161 p.
ISBN : 978-0-89573-826-4
Langues : Français (fre)
Catégories : Chimie de coordination, Chimie organométallique, Métaux de transition Tags : APPLICATIONS ORGANOMETALLIC-SYNTHESIS CARBON DIOXIDE Index. décimale : B-D Résumé : This book reviews the activation of carbon dioxide by metal complexes, covering all aspects of organometalic chemistry, homegeneous catalysis, and indstrial applications. It demonstrate the close relationship between stoichiometric and catalytic reactions of CO2 with organic substrates invlovingtransition metal complexes. The author illustrates the fascination of this research area which has become the focus of attention for numerous chemical disciplines: bio-, electro-, photo- and polymer chemistry. He reveals that in CO2 chemistry many novelties are still to be discovered, and that completely new synthetic routes to industrially interesting compounds seem possible. 800 references up to 1987 provide a convenient and comprehensive overview of the subject. Note de contenu : "* Carbon dixide as raw material
* Aims of the present review
* Stoichiometric reactions of carbon dioxide on transition metal centers
* Catalytic reactions of carbon dioxide at transition metal complexes"Cote : B-D208 Num_Inv : 3596 Localisation : LCC (SdS) Exemplaires(1)
Code-barres Cote Support Localisation Section Disponibilité 3596 B-D208 Texte imprimé Bibliothèque Livre Disponible